Aventis Pharma S.a.

Sanofi

Sanofi-a Ventis Deutschland Gmbh

Bayer Cropscience S.a.

Novexel Sa

Eric Bacque

Baptiste Ronan

Michel Tabart

Jean-Claude Barriere

Pascal Desmazeau

Fabrice Viviani

Serge Mignani

Antony Bigot

Catherine Souaille

Jean-Christophe Carry

Frank Halley

Yves Ribeill

Antonio Ugolini

Claude Guyon

Gilles Dutruc-Rosset

Dominique Damour

Gilles Doerflinger

Youssef El Ahmad

Jean-Philippe Letallec

Sylvie Wentzler

Conception Nemecek

Eva Albert

Jean-Luc Malleron

Jean Bouquerel

Daniel Achard

Serge Grisoni

Vincent Leroy

Jean-Pierre Leconte

Gérard Puchault

Jean-Pierre A Vors

Laurent Schio

Alain Villier

Michel Evers

Patrick Mailliet

Youssef El-Ahmad

Marcel Patek

Bruno Filoche-Romme

Martin Smrcina

Herv&eacute; Bouchard

Anil Nair

Corinne Terrier

Maurice Brollo

Gilbert Marciniak

Anke Steinmetz

Bertrand Vivet

Alain Commer&ccedil;on

Kirsten Bjergarde

Karl Andreas Karlsson

Chantal Carrez

Didier Benard

Emmanuel Conseiller

Annie Clauss

Luc Bertin

Mark Dodson

Bruno Filoche-Rommé

Guy Pantel

St&eacute;phane Mutti

Francisco Nieto-Roman

Christophe Daubi&eacute;

Andre Zimmermann

William Henri Barriere, Legal Representative

G&eacute;rard Puchault

Baptisite Ronan

Nathalie Hélène Barriere, Legal Representative

Martha Ackerman-Berrier

François Vallee

Bruno Filoche-RommÉ

André Zimmermann

The disclosure relates to compounds of formula (I): wherein, A, W, X, and Ra are as defined in the disclosure, and salts thereof, and to pharmaceutical compositions comprising said compounds, to processes for preparing them, and to their use as medicaments, in particular as MET inhibitors.

6-triazolopyridazine sulfanyl benzothiazole derivatives as MET inhibitors

The invention relates to compounds of the formula:  or their racemic, enantiomeric or diastereoisomeric isomers, or pharmaceutically acceptable salts of the compounds of formula I or the racemic, enantiomeric or diasteroisomeric isomers.

1,2,3,4-tetrahydro-pyrimido(1,2-a)pyrimidin-6-one derivatives, preparation thereof, and pharmaceutical use thereof

The present invention relates to imidazolone derivatives of formula (I) to methods of preparing such derivatives, intermediates thereto, pharmaceutical compositions comprising such derivatives, and methods of inhibiting protein kinase, and methods of treatment comprising administration of such derivatives.

Imidazolone derivatives, preparation thereof as drugs, pharmaceutical compositions, and use thereof as protein kinase inhibitors, in particular CDC7

The disclosure relates to compounds of formula (I): which modulate the activity of proteins, particularly kinases, and to compositions containing the same, and to the use thereof as medicaments, in particular as anticancer agents.

7-substituted aza-indazoles, compositions containing same, production method and use thereof

This invention relates to isoindole derivates of Formula I to pharmaceutical compositions comprising such derivatives, and to methods of treatment comprising administering of such derivatives.

Isoindole derivatives, compositions containing same, preparation thereof and pharmaceutical uses thereof in particular as inhibitors of chaperone protein Hsp90 activities

The disclosure relates to substituted pyrazolo-pyridines, compositions containing them, methods for the production thereof, and to their use as medicaments, in particular, as anticancer agents.

Substituted pyrazolopyridines, compositions containing them, method for the production thereof, and their use

The invention relates to compounds of formula (I): wherein Ra, R1, Ar, L, A, W, Y, and Z are as defined in the disclosure; to compositions containing them; and to the preparation and use thereof, in particular as anticancer agents.

Substituted pyrrolopyridines, compositions containing them, manufacturing process therefor and use thereof

The disclosure concerns substituted pyrroles of formula (I): wherein A, L, Ar, R1, R2, R5, and Ra are as defined in the disclosure, compositions containing the same, methods for making the same and uses thereof, in particular as anti-cancer agents.

Substituted pyrroles, compositions containing same, method for making same and use thereof

Compounds of formula (I): wherein R1, R5, R6, R7, Ar, L, A, and Q are as defined in the description, and to salts thereof, to compositions containing them, to the process for preparing them, and to their use as medicinal products, in particular as anticancer agents.

Substituted indoles, compositions containing them, method for the production thereof and their use

The invention concerns a method for preparing compounds of general formula (I) wherein: n, Q, Q, X, X, Y and Z are as defined in the description. 

Method for preparing derivatives of 3-hydroxypicolinic acid

The disclosure concerns substituted imidazoles and pyrroles, compositions containing the same, the preparation thereof, and the use thereof as medicaments, particularly as anti-cancer agents.

Substituted pyrroles and imidazoles, compositions containing same, manufacturing process therefor and use thereof

Quinolylpropylpiperidine derivatives of general formula (I) in which Ris hydrogen or fluorine, Ris carboxyl, carboxymethyl or hydroxymethyl, Ris alkyl substituted either with phenylthio optionally substituted with halogen, hydroxyl, alkyl, alkyloxy, trifluoromethyl, trifluoromethoxy, carboxyl, alkyloxycarbonyl, cyano or amino, or with cycloalkylthio (3 to 7 members) optionally substituted with halogen or trifluoromethyl, or with heteroarylthio (5 to 6 members and 1 to 4 heteroatoms chosen from N, O and S), optionally substituted with halogen, hydroxyl, alkyl, alkyloxy, trifluoromethyl, trifluoromethoxy, carboxyl, alkyloxycarbonyl, cyano or amino or Ris propargyl substituted by phenyl or heteroaryl as defined above and Ris alkyl, alkenyl-CH&#x2014; or alkynyl-CH&#x2014;, cycloalkyl or cycloalkylalkyl, in their various isomeric forms, separate or as mixtures, and also their salts, their preparation process and intermediates and the compositions containing them. These novel derivatives are potent antibacterial agents 

Quinolylpropylpiperidine derivatives, intermediates and compositions containing them, and preparation therefor

The present invention discloses and claims pharmaceutical compositions comprising Group A streptogramin derivatives of formula (I) and salts thereof in combination with at least one natural group B streptogramin derivative 

Streptogramin derivatives and compositions thereof

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Gif sur Yvette, France

Eric Bacque