Ascensia Diabetes Care Holdings Ag

Bayer Healthcare LLC

Emerson Climate Technologies Gmbh

Eric Anthony Maurer

Huan-Ping Wu

Christine D Nelson

Hope Spradlin

Joseph E Perry

Christine G Trippel

Huan Ping Wu

Sung-Kwon Jung

Weiping Zhong

Paul L Fullenkamp

Bern Everett Harrison

Roxana E L Ruxanda

Jesús Ángel Nohales Herraiz

Francis Beckers

Vincent Cloosen

Laurent Grignard

Ping Wu

Carl Joseph Lachey

Hope G Spradlin

Wieping Zhong

A biosensor system determines analyte concentration from an output signal generated from a light-identifiable species or a redox reaction of the analyte. The biosensor system compensates at least 50% of the total error in the output signal with a primary function and compensates a portion of the remaining error with a residual function. The amount of error compensation provided by the primary and residual functions may be adjusted with a weighing coefficient. The compensation method including a primary function and a residual function may be used to determine analyte concentrations having improved accuracy from output signals including components attributable to error.

Residual compensation including underfill error

A compressor may include a non-orbiting scroll, an orbiting scroll, a driveshaft and an Oldham coupling. The orbiting scroll meshingly engages the non-orbiting scroll. The driveshaft includes a crankpin engaging the orbiting scroll and driving the orbiting scroll in an orbital path relative to the non-orbiting scroll. The Oldham coupling may include an annular body and a plurality of first keys extending from the annular body and slidably received in slots formed in the orbiting scroll. Each of the first keys may include a first post and a first cap attached to the first post. The first posts may be integrally formed with the annular body from a first material. The first caps may be formed from a second material.

Compressor with Oldham assembly

Biosensor systems including a measurement device and test sensors including at least three independently addressable electrodes, with at least two of the electrodes being substantially chemically isolated are disclosed. One or more working electrodes may be combined with two or more counter electrodes. The two or more counter electrodes may operate at different potentials to provide for multi-analyte electrochemical analysis. Analysis methods are provided to perform multi-analyte electrochemical analysis and test sensors are provided having resistance to chemical mixing between secondary analysis regions.

Multi-region and potential test sensors, methods, and systems

A compressor may include a non-orbiting scroll, an orbiting scroll, a driveshaft and an Oldham coupling. The orbiting scroll meshingly engages the non-orbiting scroll. The driveshaft includes a crankpin engaging the orbiting scroll and driving the orbiting scroll in an orbital path relative to the non-orbiting scroll. The Oldham coupling may include an annular body and a plurality of first keys extending from the annular body and slidably received in slots formed in the orbiting scroll. Each of the first keys may include a first post and a first cap covering at least a portion of the first post. The first posts may be integrally formed with the annular body from a first material. The first caps may be attached to the first posts and formed from a second material.

The present invention relates to electrochemical sensor strips and methods of determining the concentration of an analyte in a sample or improving the performance of a concentration determination. The electrochemical sensor strips may include at most 8 &#x3bc;g/mmof a mediator. The strips, the strip reagent layer, or the methods may provide for the determination of a concentration value having at least one of a stability bias of less than &#xb1;10% after storage at 50&#xb0; C. for 4 weeks when compared to a comparison strip stored at &#x2212;20&#xb0; C. for 4 weeks, a hematocrit bias of less than &#xb1;10% for whole blood samples including from 20 to 60% hematocrit, and an intercept to slope ratio of at most 20 mg/dL. A method of increasing the performance of a quantitative analyte determination also is provided.

Electrochemical test sensor

A biosensor system including the underfill management system determines the analyte concentration in a sample from the at least one analytic output signal value. The underfill management system includes an underfill recognition system and an underfill compensation system. The underfill recognition system determines whether the test sensor initially is substantially full-filled or underfilled, indicates when the sample volume is underfilled so that additional sample may be added to the test sensor, and starts or stops the sample analysis in response to the sample volume. The underfill recognition system also may determine the initial degree of underfill. After the underfill recognition system determines the initial fill state of the test sensor, the underfill compensation system compensates the analysis based on the initial fill state of the test sensor to improve the measurement performance of the biosensor system for initially underfilled test sensors.

Underfill management system for a biosensor

Carbon dioxide compressors having one or more coatings with wear surfaces having electroless surface coatings are provided. Alternatively, propane compressors are contemplated having wear surface coatings. The coating is electrolessly applied and may comprise nickel and wear resistant particles, such as boron nitride. The electroless surface coatings for use with compressor machines improve corrosion and wear resistance, as well as anti-friction properties for compressors processing COor CHcontaining refrigerants. In certain aspects, a scroll machine has an Oldham coupling and/or lower bearing comprising aluminum and has an electroless surface coating comprising nickel boron nitride particles disposed on one or more wear surfaces. In other aspects, a reciprocating compressor has a wear surface, such as on a connecting rod and/or piston coated with an electrolessly applied nickel and boron nitride particle layer. Methods for making the electroless surface coatings are also provided.

Components for compressors having electroless coatings on wear surfaces

Multi-region and potential test sensors, methods and systems

A biosensor with an underfill recognition system assesses whether to analyze a sample for one or more analytes in response to the volume of the sample. The underfill recognition system applies polling and test excitation signals to the sample. The polling signals generate one or more polling output signals, which maybe used to detect when a sample is present and to determine whether the sample has sufficient volume for analysis. The test excitation signal generates one or more test output signals, which may be used to determine one or more analyte concentrations in the sample.

Underfill recognition biosensor

The present invention relates to methods of determining the concentration of an analyte in a sample or improving the performance of a concentration determination. The electrochemical sensor strips may include at most 8 &#x3bc;g/mmof a mediator. The strips, the strip reagent layer, or the methods may provide for the determination of a concentration value having at least one of a stability bias of less than &#xb1;10% after storage at 50&#xb0; C. for 4 weeks when compared to a comparison strip stored at &#x2212;20&#xb0; C. for 4 weeks, a hematocrit bias of less than &#xb1;10% for whole blood samples including from 20 to 60% hematocrit, and an intercept to slope ratio of at most 20 mg/dL.

Growing community of inventors

Troy, OH, United States of America

Eric Anthony Maurer