Purdue Research Foundation

Sparta Biopharma Inc.

Pacers Basketball, LLC

Eric Allen Nauman

Darryl A Dickerson

Anne Dye Zakrajsek

Evan Louis Breedlove

Andrew J Zakrajsek

Steven Forrest Son

Dushyanth R Surakanti

Adam B Yanke

Travis E Entrop

Adam W Martinez

Dimitrios J Angelis

Thomas Michael Talavage

Kurt W S Klitzke

George Tsu-Chih Chiu

Nikhil Bajaj

Jeffrey Frederick Rhoads

Lia Antoaneta Stanciu

John H Cushman

Allison Kelly Murray

Madhi Dehestani

Michael J Heiden

Eric S Lynch

Jonathan M Childress

Haley Elizabeth Smith

Daniel J Rawson

Jennifer Anne Boehm

Rachel Nicole Berry

Jocelyn Teresia Dunn

Sami Imad Labban

Allison Jean Gleason

Quinton James Lasko

Josh Corbeil

James A Isca

Ninad Trifale

Mackenzie Tweardy

Roy Lycke

Michael Wadas

Dennis H Evans

Michael J Mueterthies

Connective tissue-to-bone interface scaffolds (e.g., ligament-to-bone interface scaffolds, tendon-to-bone interface scaffolds, etc.). These scaffolds may be a single integrated implant or may be a modular (e.g., two-part) implant system.

Connective tissue to bone interface scaffolds

A method of detecting a substance, wherein the method includes functionalizing a plurality of sensors, wherein the functionalizing the plurality of sensors comprises depositing a first material using a piezoelectrically actuated pipette system, wherein the first material includes a polymer, a receptor, and a solvent, wherein the solvent comprises dimethylformamide. The method further includes evaporating a solution of the first material wherein a residue after the evaporation comprises a functionalized chemical. Additionally, the method includes introducing a control material to a first set of sensors of the plurality of sensors using the piezoelectrically actuated pipette system. Further, the method includes introducing a test material to a second set of sensors of the plurality of sensors using the piezoelectrically actuated pipette system, wherein the test material comprises an analyte. Moreover the method includes determining a difference between a first resonant frequency shift in the first set of sensors of the plurality of sensors and a second resonant frequency shift in the second set of sensors of the plurality of sensors.

Method of detecting a substance

Bioresorbable porous biocomposites for orthopaedic applications. In an exemplary embodiment of a resorbable orthopaedic implant of the present disclosure, the implant comprises a porous alloy of at least a first metal and a second metal sintered together, the alloy configured to resorb into a body at substantially an atomic level without flaking off, wherein a porosity of the implant is defined by a first plurality of interconnected holes having a first range of sizes.

Bioresorbable porous metals for orthopaedic applications

Systems and devices for use as lower leg prosthetic devices that include a foot portion having anterior and posterior ends and a first surface having a protrusion that protrudes therefrom adjacent the posterior end of the foot portion, has a semispherical or hemispherical surface with a passage therethrough extending laterally relative to the foot portion. The systems and devices further include a toe portion pivotally coupled to the anterior end of the foot portion, and a plate portion configured to couple to an attachment device and thereby be functionally secured to a user. The plate portion has a recess configured to couple with the protrusion of the foot portion. A cylindrical rod is located within the lateral passage of the protrusion and has ends protruding therefrom on oppositely-disposed of the protrusion. The plate portion is pivotally coupled to the ends of the rod on oppositely-disposed lateral sides of the protrusion.

Lower leg prosthetic systems and devices

One or more devices, methods, and systems implementing one or more techniques for use of one or more sport balls and/or evaluations of handling one or more sport balls are disclosed. One or more techniques may include a sport ball having one or more pressure sensors configured to generate one or more force values between the one or more pressure sensors and a sport ball user upon use/engagement of the sport ball with the user. One or more techniques may include a processor configured to determine at least one handling value, perhaps based upon the one or more force values.

Technologies for a sport ball and for evaluation of handling a sport ball

Membraneless electrochemical cells and batteries are disclosed. The cells comprise electrolyte solutions that are not miscible. The cells and batteries disclosed herein may be used to deliver electricity to process applications.

Electrochemical cells and batteries

A compound for protection of an object from a blast or shock wave. The compound include a matrix material and at least a first and second sets of inclusions in the matrix material that differ in size, quantity, shape and/or composition in a direction through the impact-absorbing material, the combination of which contributes to the ability of the material to exhibit at least one property that changes as the inclusions are deformed in response to a blast or shock wave.

Method of making a blast or shock wave mitigating material

A double-shell helmet is disclosed. The double-shell helmet includes an outer shell, an impact absorbing material layer affixed to the outer shell on a first side of the impact absorbing material layer, an inner shell affixed to the impact absorbing material layer on a second side of the impact absorbing material layer opposite the first side of the impact absorbing material layer, and a foam layer affixed to the inner shell.

Dynamic load-absorbing materials and articles

Dynamic load-absorbing materials suitable for use as cushion-type and armor-type materials, for example, of types that can be incorporated into protective gear, equipment, armor, vehicles, and various other structures, or used for the isolation and dissipation of vibratory loads, such as vibration isolators used to support avionic equipment. The impact-absorbing materials include a matrix material () and at least first and second sets of inclusions (which can be either included material or voids) () in the matrix material () that define a hierarchy of inclusions () in the matrix material (). The inclusions () differ in size, quantity, shape and/or composition in a direction through the impact-absorbing material, the combination of which contributes to the ability of the material to exhibit at least one property that changes as the inclusions () are deformed under load.

Dynamic load-absorbing material and articles

The present invention provides a cancellous bone scaffold to use in the replacement or repair of connective tissue such as ligaments and tendons. The cancellous bone scaffold has a fully demineralized segment with at least one adjacent mineralized end segment.

Demineralized cancellous bone scaffolds

Disclosed are bioscaffolds and methods for use in soft tissue repair.

Compositions and methods for repair or regeneration of soft tissue

A sleeve that provides mechanical stimulation to the arm to prevent bone density loss. A primary goal of this product is to prevent bone density loss that occurs during extended space travel. For one embodiment, only the predefined frequency specifications had to be met (between 40 Hz and 60 Hz). By meeting these frequencies for a duration of 30 minutes the product will theoretically prevent the loss of bone density. Additionally, clinical trials will need to be conducted before this product can be marketed. The product includes of several mechanical vibrators attached to a sleeve. The vibrators are small unbalanced-mass motors which are similar to those found in cell phones. The motors are encased in dome shaped housings designed to reduce lateral vibrations along the arm. The product is controlled using an Arduino board attached to the sleeve that actuates the motors. The motors, in turn, provide the specified frequency to the arm for 30 minutes. The spacing of the motor housings was determined from PEA simulations. This resulted in the motors being spaced 2 in apart along the arm at 90&#xb0; increments around the axis of the arm. The controller has a display that allows for user interaction and includes a session timer. In addition, this product is contemplated for use in reducing muscle atrophy, eliminating bed sores, and treating other ailments that can result from sedentary behavior.

Therapeutic method and apparatus using mechanically induced vibration

Growing community of inventors

West Lafayette, IN, United States of America

Eric Allen Nauman