Central Glass Company, Limited

Eri Nishizawa

Shinya Akiba

Ryo Nadano

Asami Inazu

A purification method of desflurane (difluoromethyl-1,2,2,2-tetrafluoroethyl ether of the formula (1)) includes bringing a mixture containing desflurane and a trihalomethane into contact with a base in the presence of a phase transfer catalyst, thereby decomposing the trihalomethane. By this method, only the trihalometane contained as a by-product in the desflurane is decomposed without causing decomposition of the desflurane, whereby the desflurane is obtained with high purity. 

Purification method and production method of difluoromethyl-1, 2, 2, 2-tetrafluoroethyl ether

Disclosed is an industrial method for efficient production of an &#x3b1;,&#x3b1;-difluoroaldehyde compound, which includes reaction of an &#x3b1;,&#x3b1;-difluoroacetate with hydrogen gas (H) in the presence of a ruthenium catalyst and a base. By the adoption of specific reaction conditions (catalyst, base, pressure etc.), it is possible to produce the target &#x3b1;,&#x3b1;-difluoroaldehyde compound with a high conversion rate and high selectivity.

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Kawagoe, Japan

Eri Nishizawa