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Istituto Farmacologico Serono S.p.a.

Enzo Marchetti

Umberto Bucciarelli

The extemperaneous preparation of liposomes incorporating englobed therapeutically active substances is effected by introducing an aspirated phopholipid emulsion into a container containing the active substance as a dry powder or lyophilate.

Process for the extemporaneous preparation of liposomes

2-Aminomethyl- and 2-(2-aminoethyl)-substituted 4,5-diphenyloxazoles of the general formula ##STR1## and salts thereof with non-toxic organic or inorganic acids having antiphlogistic, analgesic, anti-aggregant and local anaesthetic properties with low toxicity are provided, as well as processes for preparing them.

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Rome, Italy

Enzo Marchetti