Sigea S.r.l.

Montedison S.p.a.

Siega S.r.l.

Enzo Alessio

Giovanni Mestroni

Gianni Sava

Alberta Bergamo

Grazia Zassinovich

Elisabetta Iengo

Sonia Zorzet

A class of anionic and neutral complexes of ruthenium (II) containing nitrogen oxide (NO) and optionally a nitrogen ligand is described; a process for their preparation is also described. The preparation process includes the use of starting complexes of ruthenium (III) which are reacted with suitable reagents so as to obtain complexes containing NNO coordinated to ruthenium (II). Additional substitution reactions allow the introduction of new groups that coordinate to the ruthenium atom, among which some nitrogen ligands.

Anionic and neutral complexes of ruthenium (II) with nitrogen oxide

A class of anionic and neutral complexes of ruthenium (II) containing nitrogen oxide (NO) and optionally a nitrogen ligand is described; a process for their preparation is also described. The preparation process includes the use of starting complexes of ruthenium (III) which are reacted with suitable reagents so as to obtain complexes containing NO coordinated to ruthenium (II). Additional substitution reactions allow the introduction of new groups that coordinate to the ruthenium atom, among which some nitrogen ligands.

New ruthenium dimeric complexes with high antimetastatic and antitumour activity and remarkable chemical stability are described.

Ruthenium dimeric complexes suitable as antimetastatic and antineoplastic agents

A salt of an anionic complex of Ru(III) with an ammonium cation fof formula (I),

Salts of anionic complexes of RU(III), as antimetastatic and antineoplastic agents

A process is herein described for catalytically reducing nitroaromatic compounds by displacement of hydrogen from carbon monoxide and water or from synthesis gas to nitroaromatic compounds, the catalytic reduction being catalyzed by complexes of rhodium, iridium, ruthenium and osmium; said process is characterized in that the CO+H.sub.2 O system or the (CO+H.sub.2)+H.sub.2 O system is caused to react with a nitroaromatic compound of formula:

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Trieste, Italy

Enzo Alessio