Other

Planton Gmbh

Zeneca Limited

Beiersdorf Ag

Gist-brocades N.v.

Enno Christophers

Jens-Michael Schroder

Oliver Wiedow

Udo Hoppe

Florian Wolf

Michael Derek Edge

Jens Schroder

David Pioli

Jens Schroeder

Jens-M Schr&ouml;der

Juergen Harder

Jurgen Harder

The invention relates to proteins, notably SAP-2 and SAP-3, having an antibiotic action. The invention also relates to a method for purifying certain antimicrobial proteins, as well as to a use of said antimicrobial proteins for antibiotic therapy or to a use of cells which were transfected with a DNA which codes for the proteins provided for in the invention.

Human antibiotic proteins

Polypeptides, in particular the polypeptide of formula I: and analogues thereof which possess inhibitory activity against human leukocyte elastase. The polypeptides may be obtained by expression using plasmidic expression systems in hosts such asand yeast, the polypeptide of formula I being also obtainable from psoriatic plaques.

Nucleic acids

Cosmetic preparations containing vertebrate proteins and having antibacterial, antimycotical and antiviral action

polypeptides and polypeptide analogues

Polypeptides, in particular the polypeptide of formula I: ##STR1## and analogues thereof which possess inhibitory activity against human leukocyte elastase. The polypeptides may be obtained by expression using plasmidic expression systems in hosts such as E. Coli and yeast, the polypeptide of formula I being also obtainable from psoriatic plaques.

Polypeptides and polypeptide analogues

A substance is prepared having interleukin-8 inhibiting activity by extracting psoriatic scales and separating the extract on several successive HPLC columns, using an assay for IL-8i activity based on the inhibition of myeloperoxidase release and/or of the neutrophil chemotaxis of a reference sample. The substance is suitable for the preparation of anti-inflammatory medicines.

Substance with interleukin-8 inhibiting activity and process for its

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Kiel, Germany

Enno Christophers