Jiangsu Kanion Pharmaceutical Co., Ltd.

Jiangsu Kanion Parmaceutical Co. Ltd

Enli Zhou

Wei Xiao

Zhenzhong Wang

Hanfei Hu

Chenfeng Zhang

Xiujuan Chang

Xiaodong Kang

Yongxiang Wang

Yun Wu

Zeyu Cao

Aditerpene lactone composition is provided. The extract can lower the neurological function score of a cerebral ischemia-reperfusion rat, reduce the cerebral ischemia area and the water content after brain tissue edema, improve SOD activity, and decrease the MDA content. The composition can inhibit rabbit platelet aggregation induced by PAF and ADP inducers at different time points so as to reduce the maximum aggregation rate. In addition, experiments show that the effect of each monomer compound in thediterpene lactone composition is significantly increased at certain proportion.

Gingko diterpene lactone composition

Aditerpene lactone composition is provided. The composition has the effect of improving a depressive state. The composition can prolong a tail flick interval time and a swimming interval time of a mouse to different degrees and can also increase the frequency of escaping from electric shock to different degrees. The additional addition of a certain amount of ginkgolide C, ginkgolide J, and ginkgolide L greatly enhances the effect of improving the depressive state. It is further proved through experiments that after the provision of thediterpene lactone composition, indexes, such as SOD, MDA, GSH, and TAC, can be improved to different degrees. For example, after the addition of a certain amount of ginkgolide C, ginkgolide J, and ginkgolide L, the improving effect gets more obvious, the oxidative stress level can be better improved, and the oxidative damage can be relieved.

Ginkgo diterpene lactone composition

Growing community of inventors

Jiangsu, China

Enli Zhou