Graybug Vision, Inc.

Other

Emissions Technology, Inc.

Graybug Visioon, Inc.

Emmett Manuel Cunningham

Jeffrey L Cleland

John G Bauman

Ming Yang

Nu Hoang

George M Malouf

Russ Webster

Xiong Li

Kevin Hong

The present invention provides new prodrugs of therapeutically active compounds, including oligomeric prodrugs, and compositions to treat medical disorders, for example glaucoma, a disorder or abnormality related to an increase in intraocular pressure (IOP), a disorder requiring neuroprotection, age-related macular degeneration, or diabetic retinopathy.

Drugs and compositions for the treatment of ocular disorders

The disclosure describes prodrugs and derivatives of prostaglandins, carbonic anhydrase inhibitors, kinase inhibitors, beta-adrenergic receptor antagonists and other drugs, as well as controlled delivery formulations containing such prodrugs and derivatives, for the treatment of ocular disorders.

Compounds and compositions for the treatment of ocular disorders

Embodiments of the invention provide catalysts for hydrocarbon oxidation. One embodiment of the invention provides a catalyst for hydrocarbon oxidation comprising: a liquid medium including aromatic hydrocarbon 150; bis(2,4-pentanedionato)platinum; bis(2,4-pentanedionato)palladium; ferrocene; magnesium 2-ethylhexanoate; and cerium (III) 2-ethylhexanoate, rhenium in an organo-metallic compound, or both.

Catalysts for hydrocarbon oxidation

A system and method for delivering catalytic molecular structure to a combustion chamber is disclosed. Catalyst base materials are reduced to a micronic fog by a device using the ultrasonic vibration of a piezoelectric disc. The liquid base materials evaporate instantly upon entering the engines air stream therefore releasing pure catalyst molecules into the combustion zone, thus reducing the time taken for catalytic combustion to the lowest denominator possible and allowing for the greatest effect achievable. This further reduces the amount of catalyst needed in the base solution compared to any other type of device or additive. The system also allows a user to control the delivery rate of the catalyst to the combustion chamber.

Catalyst delivery system and method therefor

Efficient fuel combustion catalyst delivery device and method are provided. A fuel combustion catalyst delivery device includes a storage vessel that contains a liquid. The liquid includes one or more catalytic materials. The storage vessel is attached to a nebulizer that can convert the liquid to an aerosol to be delivered into an air intake of a combustion zone. The aerosol can accelerate fuel combustion. The storage vessel and the nebulizer are made from materials suitable to be exposed to the liquid and the aerosol. The storage vessel and the nebulizer are also suitable to be placed in proximity to the combustion zone such as an engine compartment so that the aerosol can be delivered into the air intake of the combustion zone easily and effectively. The surfaces of the delivery device exposed to the liquid or the aerosol may be made of corrosion-resistant or inert materials if the liquid is acidic. The surfaces of the delivery device exposed to the liquid or the aerosol may be also made from materials that produce substantially no contaminants into the liquid. The nebulizer may convert the liquid to an aerosol at a rate between once per second and one hundred times per second. The nebulizer may have holes for passing the liquid where each of the holes has a size not greater than about 10 &#x3bc;m. The delivery device can deliver up to 500 ml or more of liquid as aerosol over 500 hours of operation.

Fuel combustion catalyst microburst aerosol delivery device and continuous and consistent aerosol delivery device

Efficient and effective fuel combustion catalyst delivery apparatus is disclosed. A fuel combustion catalyst delivery apparatus may include a receptacle containing a material such as a liquid. The liquid may include one or more catalytic materials. The apparatus may further include a vibration pump configured to convert the liquid to an aerosol to be delivered into an intake air of a combustion zone, a pressure equalizer configured to maintain the pressure level of the receptacle at about the same pressure level as that of the intake air of the combustion zone, and a liquid delivery device configured to deliver the liquid to the vibration pump. The apparatus may further include an electronic control module and a mounting bracket or a docking station. The electronic control module may be used to control the vibration pump. The apparatus may further include a pressure sensor for sensing the pressure level of the intake air of the combustion zone so that the vibration pump can regulate the delivery rate of the liquid into the intake air as the aerosol based on the pressure level of the intake air. The vibration pump may be also configured to regulate the delivery rate of the liquid into the intake air as the aerosol, based on an actual fuel consumption rate in the combustion zone.

Growing community of inventors

Phoenix, AZ, United States of America

Emmett Manuel Cunningham