Commissariat &#xc0; L'&#xc9;nergie Atomique Et Aux &#xc9;nergies Alternatives

Intelligence Artificielle Applications

Commissariat a L'energie Atomique

Emmanuelle Schultz

Cedric Allier

Mathieu Dupoy

Pierre Montmeat

Thomas Bordy

Francois Perraut

Cédric Allier

Michel Roch

Damien Decq

Veronique Rebuffel

Pierre Marcoux

Severine Vignoud

Selimen Benahmed

François Perraut

Frédéric Suard

David Peyrade

Anne Planat-Chretien

Anthony Larue

Jean-Charles Baritaux

Séverine Vignoud

Samy Strola

Valentin Genuer

Michael Descamps

Nicolas Paul

Marianne Guillemot

Michaël Descamps

A device and method for observing an object, in particular a biological object includes a light source able to illuminate a sample. Under the effect of the illumination, the object emits back-scattered radiation that propagates to a screen, the area of which is larger than 100 cm. The projection of the back-scattered radiation onto the screen forms an image representative of the back-scattered radiation, called a scattergram. An image sensor allows an image representative of the scattergram formed on the screen to be acquired.

Device and method for observing the radiation backscattered by an object

A device and method for observing an object, in particular a biological object, includes a light source able to illuminate a sample, and a screen lying between the light source and the object. The screen includes an aperture, through which propagates the illuminating beam produced by the light source and propagating toward the screen. Under the effect of the illumination, the object emits back-scattered radiation that propagates to the screen, the area of which is preferably larger than 100 cm. The projection of the back-scattered radiation onto the screen forms an image representative of the back-scattered radiation, called a scattergram. An image sensor allows an image representative of the scattergram formed on the screen to be acquired.

Method for observing an object

The invention is an iterative method for acquiring a spectrum of a particle that is subjected to an illumination. It may in particular be a Raman spectrum. The method includes successively acquiring spectra that are what are called elementary spectra. These elementary spectra are combined to form a combined spectrum, which may be obtained by summing said elementary spectra. With each elementary spectrum is associated an acceptance criterion that is representative of a variation between said elementary spectrum and the elementary spectra acquired beforehand. Depending on this acceptance criterion, the elementary spectrum is either rejected, or accepted, in which case it is added to the combined spectrum. The invention makes it possible to guard against a degradation of the particle under the effect of an excessive exposure to said illumination.

Method for acquiring a spectrum

A system is provided for observing objects on a substrate which includes a light source that emits polarized light rectilinearly along a first direction, a holder that receives said substrate having a surface and includes objects, wherein at least one of the holder or the substrate are translucent or opaque, a detector that collects the backscattered light from the interaction between the light emitting by the light source and the objects, a polarization splitter and a quarter-wave plate wherein the polarization splitter and the quarter-wave plate are arranged so that the polarization splitter directs light towards the substrate through the quarter-wave plate, and wherein the light forms a beam and the system modifies the size of the beam. The system thus allows one to observe objects on a non-transparent substrate.

System for observing objects

A method for regulating the relative position of an analyte of a sample () in relation to a light beam (F) includes the illumination of the analyte of the sample () with the light beam (F), capturing by an imaging device () a transmission image of the beams scattered by the analyte of the sample () in order to establish a diffraction pattern, and modifying the relative position of the analyte of the sample () in relation to the light beam (F) according to at least one property of the diffraction pattern.

Method for regulating the relative position of an analyte in relation to a light beam

Provided is a system for detecting analytes of interest present in a gas sample, including a layer of porous material, positioned at the surface of a substrate so as to extend longitudinally along a fluidic flow path of the gas sample, said porous material containing a plurality of probe molecules, each probe molecule being able to react with the analyte of interest by causing a change in the spectral properties of said probe molecule. Also included is a a pump for generating a flow of the gas sample along the fluidic path so that the gas sample comes into contact with said layer of porous material. The system also includes at least one optical detection device capable of successively detecting, at distinct detection areas of said porous material layer distributed along said fluidic path, a change in the spectral properties of at least one of said probe molecules.

System and method for detecting analytes present in a gas sample

The invention relates to a method for assaying a biological or chemical sample comprising the following steps:

Method for dosing a biological or chemical sample

Growing community of inventors

Saint Egreve, France

Emmanuelle Schultz