Ge Healthcare Bio-sciences Ab

Cytiva Sweden Ab

Emmanuel Macedo

Karol Lacki

James Van Alstine

Rolf Hjorth

Gunnar Malmquist

Jamil Shanagar

Ann-Christin Magnusson

Lena Maria Sandberg

Bjorn Johan Lundgren

Hans O Johansson

The present invention relates to a method and system for aseptic material transfer from a storage container to a bioreactor. More precisely the invention relates to a method and system for aseptically transferring dry material, such as microcarriers for cell cultivation, to a bioreactor, comprising transferring microcarriers from a first container housing said microcarriers to a bioreactor for cell cultivation via r transfer tubing connecting the first container to the bioreactor, wherein the transfer is accomplished with pressurized air or gas supplied to the container.

Method and system for cell cultivation

The present invention relates to a liquid mixture comprising a first polymer, which is a poly(acid), a second polymer, which is a poly(ether), and at least one salt, wherein the molecular weight of the poly(acid) is in the range of 1000-100,000 Da. The second polymer is selected to be capable of forming immiscible aqueous phases in the presence of the poly(acid) and salt. The poly(acid) may be selected from the group consisting of poly(acrylic acid) and poly(methacrylic acid), and the second synthetic polymer may comprise ethylene oxide. The invention may be used for separation of biomolecules, cells or particles.

Polymer two phase system and use thereof

Growing community of inventors

Uppsala, Sweden

Emmanuel Macedo