Ethicon, Gmbh

Cilag International Gmbh

Pharmacia Ab

Agouron Pharmaceuticals, Inc.

Sensile Medical Ag

Emmanuel Gremion

Amir Feriani

Joël Fontannaz

Lukas Glutz

Frederick L Estera

Chester O Baxter, Iii

Charles J Scheib

Jeffrey David Messerly

William Bruce Weisenburgh, Ii

Michael J Stokes

Rudolph Henry Nobis

Ryan M Asher

Benjamin D Dickerson

Jacob Spencer Gee

David James Cagle

Benjamin M Boyd

Rafael J Ruiz Ortiz

Omar E Rios Perez

Hans O Himbert

Mathew D Clopp

Carl J Draginoff, Jr

Karalyn R Tellio

Scott R Bingham

Alain Saurer

Daniel Siegfried

Christopher Coyne

Bohdan Pavlu

Beat Villiger

Fabian Bürli

Thomas Hulliger

Frédéric Weibel

Ben Crook

Christian Péclat

Joel Fontannaz

Stefan K&auml;ser

Christian P&eacute;clat

A drug delivery device (), comprising a delivery unit () in the form of a disposable single use part and a base unit () in the form of a reusable part for coupling to the delivery unit (), the delivery unit comprising a liquid flow system for pumping liquid from a drug vial or cartridge () received in the drug delivery device to an outlet of the device for transcutaneous administration of a liquid drug, the base unit including at least a power source and an electronic control system, the delivery unit and base units comprising a releasable locking mechanism including a locking shoulder () on the delivery unit that engages a complementary locking shoulder () on the base unit. The locking mechanism comprising an unlocking actuator that may be actuated to release the locking shoulder () from the complementary locking shoulder (). The device further comprises a coupling member () on the delivery unit that engages a complementary coupling member () on the base unit, at least one of the coupling member and complementary coupling member comprising at least one elastic arm () with a protuberant portion () at a free end thereof, the protuberant portion () having a rearwardly inclined taper () that engages a complementary taper on a complementary protuberant latch portion () of the other of said coupling member and complementary coupling member, configured to provide a pulling force (F) between the base unit and the delivery unit to draw them together in a tight fit without play.

Drug delivery device

A surgical apparatus comprises a body, a user input feature, a shaft assembly, an end effector, and a blade cooling system. The end effector comprises a clamp arm and an ultrasonic blade that may be coupled with an ultrasonic transducer. The clamp arm is configured to pivot toward and away from the ultrasonic blade. The cooling system is operable to deliver liquid coolant to the ultrasonic blade to thereby cool the ultrasonic blade. The user input feature is operable to both actuate the clamp arm and actuate the cooling system.

Features to drive fluid toward an ultrasonic blade of a surgical instrument

A surgical apparatus comprises a body, a shaft assembly, a rotation input assembly, and an end effector. The shaft assembly defines a longitudinal axis and a first fluid passageway. The rotation input assembly is operable to rotate the shaft assembly about the longitudinal axis. The rotation input assembly defines a second fluid passageway. The second fluid passageway is in fluid communication with the first fluid passageway. The end effector is located at a distal end of the shaft assembly. The end effector comprises an ultrasonic blade. The end effector is in fluid communication with the first fluid passageway such that the end effector is configured to receive fluid communicated through the first and second fluid passageways.

Features for communication of fluid through shaft assembly of ultrasonic surgical instrument

A surgical apparatus comprises a body, a shaft assembly, an end effector, and a blade cooling system. The shaft assembly couples the end effector and the body together. The shaft assembly comprises an acoustic waveguide and defines an interior space. The acoustic waveguide is configured to couple with an ultrasonic transducer. The end effector comprises a clamp arm and an ultrasonic blade in acoustic communication with the ultrasonic transducer. The clamp arm is configured to pivot toward and away from the ultrasonic blade. The shaft assembly comprises an inner tube configured to longitudinally translate to thereby pivot the clamp arm toward and away from the ultrasonic blade. The cooling system is operable to deliver liquid coolant a distal portion of the shaft. A trigger of the body is operable to rotate to thereby translate the ultrasonic blade into and out of the interior space of the shaft assembly to thereby cool the ultrasonic blade.

Ultrasonic surgical instrument with blade cooling through retraction

A dispensing apparatus for a liquid product, the apparatus comprising a) a housing () or frame (), b) a receptacle () for the liquid with a feed nozzle () arranged substantially stationary with respect to the housing or frame, c) a dosing chamber () having an orifice (), d) a mechanism arranged to allow at least ejection of liquid through the orifice and e) a through passage () arranged to allow the ejected liquid to pass in a direction different from the feed nozzle or opening. The mechanism comprises a mobile element arranged movable with respect to the housing or frame between at least a first position in which the orifice of the dosing chamber and the feed nozzle or opening are in flow communication and a second position in which the orifice and the through passage are in flow communication and the mechanism is arranged to allow aspiration of liquid through the orifice when the mobile element is in the first position and ejection of liquid through the orifice when the mobile element is in the second position. A method for operating the device comprises the steps of i) connecting the orifice and the nozzle or opening in flow communication, ii) filling liquid into the dosing chamber through the orifice, iii) aligning the orifice with the through passage, and iv) ejecting liquid from the dosing chamber through the orifice.

Dispensing apparatus and method for liquid products, particularly medicinal products

A device and use method for ejecting a liquid stream towards an eye, the stream moving from a proximal position towards a distal position, the device comprising a) a housing, b) a container for the liquid, c) at least one opening arranged for ejection of the stream and being in fluid communication with the container, d) a pump mechanism operable to deliver at least part of the liquid from the container through the opening to form the stream and e) an eyecup with a contact surface arranged for contact with the eye or its facial surroundings. The eyecup is arranged movable with respect to the opening or housing between at least two positions i) an active position with said eyecup contact surface at a defined safety distance to the opening and ii) a rest position with the eyecup contact surface at a position more proximal than in the active position and a sensor is arranged to allow discrimination between the positions. The pump mechanism may include a pump driver able to store cocked energy for driving the pump mechanism and at least one activation mechanism may be present and operable to initiate the device for the liquid delivery, whereby a driving mechanism is arranged to transform manual or stored energy both i) into cocked energy of the pump driver and ii) into direct or stored energy for operation of the activation mechanism.

Liquid delivery device and method of use thereof

Growing community of inventors

Echarlens, Switzerland

Emmanuel Gremion