Bracco Suisse Sa

Bracco International Bv

Emmanuel Gaud

Peter Frinking

Marcel Arditi

Anne Lassus

Tim Segers

Gilles Casqueiro

Philippe Bussat

Sibylle Pochon

Nicolas Rognin

Samir Cherkaoui

Nathalie Biolluz

A method for preparing a suspension of 'size-controlled' gas-filled microvesicles by microfluidic manufacturing techniques, which comprises using a gaseous flow comprising a first gas having high solubility in water and a second gas having low 5 solubility in water.

Preparation of size-controlled microvesicles

A method for preparing a suspension of size-controlled microparticles stabilized by a layer of amphiphilic material. The method, which may be applied to preparations using microfluidic techniques, comprises controlling the temperature of the microparticles during the preparation process and preferably while collecting the formed microparticles.

Preparation of size-controlled microparticles

A method is provided for use with an ultrasound scanner, wherein an estimate value (particularly, a power level of the ultrasound scanner that is required to apply a desired acoustic pressure level to the body-part, the acoustic pressure level that is actually applied to the body-part when a specific power level is set, an acoustic attenuation that occurs within a patient between a transducer of the ultrasound scanner and the body-part and/or the acoustic attenuation that occurs within the patient between different body-parts) is determined according to a comparison between measurement data (based on a measurement response comprising a non-fundamental component of a measurement echo signal received in response to a measurement excitation signal) and corresponding reference data. Corresponding computer program product, system, therapeutic method, and diagnostic method are also provided.

Estimation of acoustic level in-situ with non-fundamental analysis

A medical imaging system is proposed. The system includes means for providing a plurality of echo signals indicative of a response of a body part to a plurality of ultrasound pulsed waves having different acoustic pressures, the body part including a tissue being perfused with a contrast agent, and means for discriminating in the echo signals a contribution of a first type of contrast agent from a contribution of a second type of contrast agent and/or of the tissue, at least one harmonic component of the contribution of the first type of contrast agent having an acoustic power changing according to a first dependency law on the acoustic pressure and the at least one harmonic component of the contribution of the second type of contrast agent and/or of the tissue having an acoustic power changing according to at least one second dependency law on the acoustic pressure, wherein the means for discriminating includes means for significantly reducing the at least one harmonic component of the contribution of the second type of contrast agent and/or of the tissue with respect to the at least one harmonic component of the contribution of the first type of contrast agent according to the corresponding dependency laws.

Medical imaging system based on a targeted contrast agent

Growing community of inventors

La Croix-de-Rozon, Switzerland

Emmanuel Gaud