International Business Machines Corporation

Yale University

Globalfoundries Inc.

Emily R Kinser

Mukta G Farooq

Roy Rongqing Yu

Steven J Holmes

Qinghuang Lin

Nathan P Marchack

Richard Stephan Wise

Ian D Melville

Hariklia Deligianni

John Ulrich Knickerbocker

Robert Hannon

Hakeem Yusuff

Sufi Zafar

Krystyna Waleria Semkow

Huan Hu

Stacey M Gifford

Bruce Bennett Doris

Subramanian Srikanteswara Iyer

Babar Ali Khan

Richard Paul Volant

Hakeem B S Akinmade-Yusuff

Paul Stephen Andry

Jan Schroers

Candace A Sullivan

Golden Kumar

Sudesh Saroop

Cristina Camagong

JoAnn M Rolick-DiGiacomio

Themistoclis Kyriakides

Charu Tejwani

Jagannath Padmanabhan

Bhavana Bhoovaraghan

Jennifer C Clark

Kevin Shawn Petrarca

Damon B Farmer

Yun-Yu Wang

Wayne Michael Delia

Cornelia K Tsang

Darryl D Restaino

Thomas J Fleischman

William Francis Landers

Kevin R Winstel

Yu Luo

Troy Lawrence Graves-Abe

Chester T Dziobkowski

Thomas F Houghton

Hitten P Zaveri

Anthony David Lisi

Ying He

Themis Kyriakides

Dennis D Spencer

Ramona Kei

John E Drummond

Harikilia Deligianni

Sue Hallen

Mukta G Rarooq

Comelia K Tsang

Andrei Fustochenko

Jason Gerrard

A method for filtering magnetic particles includes spinning a filter including a plurality of pores within a substrate. The method further includes applying, subsequent to spinning the filter, an external magnetic field to the filter. The method includes disposing a solution including a first particle and a second particle onto the filter. The first particle includes a magnetic particle of interest. The method further includes separating the first particle from the second particle by capturing the first particle within a pore of the plurality of pores within the substrate.

Micro-machined filter for magnetic particles

A structure for monitoring and stimulation includes an external power supply unit. The structure also includes an internal hub communicatively coupled to the external power supply unit. The structure further includes a plurality of sensor modules communicatively coupled to the internal hub by a plurality of flexible interconnects. The plurality of sensor modules include three-dimensional (3D) comb sensor devices.

Three-dimensional silicon-based comb probe with optimized biocompatible dimensions for neural sensing and stimulation

A nanostructure includes a base layer including a surface. The nanostructure further includes nano-patterned features including non-random topography located on the surface of the base layer. The nanostructure also includes an encapsulating layer including a conductive material arranged on the nano-patterned features.

Nanostructure featuring nano-topography with optimized electrical and biochemical properties

In an approach, a biomedical device comprises at least one electrode, wherein the at least one electrode is coupled with a computer chip; at least two chemical sensors, wherein the at least two chemical sensors are coupled with the computer chip; the computer chip, wherein the computer chip comprises: a semiconductor substrate, and a processor; a microfluidic structure, wherein the microfluidic structure is an inert elastomeric polymer; a power supply device coupled to the computer chip; and an antenna configured to send data collected onto the computer chip to a remote server. In an approach, a processor stimulating a cell sample. A processor senses the presence of at least two types of biomolecules released by the cell sample. A processor records data collected by the at least two chemical sensors. A processor sends the recorded data to a remote server.

Medical device for stimulating and sensing bioactivity

A method for forming a nanostructure includes coating an exposed surface of a base layer with a patterning layer. The method further includes forming a pattern in the patterning layer including nano-patterned non-random openings, such that a bottom portion of the non-random openings provides direct access to the exposed surface of the base layer. The method also includes depositing a material in the non-random openings in the patterning layer, such that the material contacts the exposed surface to produce repeating individually articulated nano-scale features. The method includes removing remaining portions of the patterning layer. The method further includes forming an encapsulation layer on exposed surfaces of the repeating individually articulated nanoscale features and the exposed surface of the base layer.

A three-dimensional (3D) comb probe structure includes a carrier, a plurality of combs arranged in the carrier and spaced apart from one another, a plurality of shanks forming the combs, each shank including a base portion and a stem portion extending from the base portion, wherein sets of the shanks are joined together by the base portions thereof to form a respective comb, and a plurality of sensing elements disposed along the stem portion of each of the shanks and electrically connected to electrical contacts disposed at respective ones of the base portions. The sensing elements can include nanopatterned features on surfaces thereof forming a non-random topography.

Three-dimensional silicon-based comb probe

A biosensor includes an array of metal nanorods formed on a substrate. An electropolymerized conductor is formed over tops of a portion of the nanorods to form a reservoir between the electropolymerized conductor and the substrate. The electropolymerized conductor includes pores that open and close responsively to electrical signals applied to the nanorods. A dispensing material is loaded in the reservoir to be dispersed in accordance with open pores.

Neuro-chemical sensor with inhibition of fouling on nano-electrode

A sensing and treatment device includes an array of metal nanorod electrodes formed on a substrate, the array including first electrodes for sensing, and second electrodes for electrical pulsation. A data processing system is configured to monitor a parameter using the first electrodes and to activate the electrical pulsation in the second electrodes in accordance with a reading of the parameter.

Intelligent and disposable device for selective electrical stimulation of apoptosis

Embodiments for processing language by one or more processors are described. A plurality of document portions are detected. Each of the plurality of document portions includes text in a respective language type. The text of each of the plurality of document portions is converted to a standardized language type. A language processing method is caused to be performed on the plurality of document portions after the converting of the text of each of the plurality of document portions to the standardized language type.

Methods and systems for processing language with standardization of source data

Lenses and methods for adjusting the focus of a lens include dividing multiple light sensors in a lens into four quadrants. A position of the lens relative to occlusion along a top and bottom edge of the lens is determined based on numbers of bits in respective bit sequences from light sensors in respective regions of the lens. An optimal focal length for the lens is determined based on the position of the lens. The focal length of the lens is adjusted to match the optimal focal length.

Saccade and vergence tracking for distance auto focus adjustment

Aspects include methods of fabricating antibacterial surfaces for medical implant devices including patterning a photoresist layer on a silicon substrate and etching the silicon to generate a plurality of nanopillars. Aspects also include removing the photoresist layer from the structure and coating the plurality of nanopillars with a biocompatible film. Aspects also include a system for preventing bacterial infection associated with medical implants including a thin silicon film including a plurality of nanopillars.

Antibacterial medical implant surface

Growing community of inventors

Poughkeepsie, NY, United States of America

Emily R Kinser