Pfizer Corporation

Dow Agrosciences LLC

Biomed Valley Discoveries, Inc.

Albany Molecular Research, Inc.

Mirati Therapepeutics, Inc.

Emily Marie Rigsbee

Ekaterina Albert

Mark Maloney

Stephen Anderson

Shu Yu

Elaine Greer

Gary D Crouse

Thomas Clarence Sparks

Noormohamed Mohamed Niyaz

CaSandra Lee McLeod

William Thomas Lambert

Dean Welsch

Gary DeCrescenzo

Annette Vitale Brown

Jon Gordon Selbo

James M Renga

David Anthony Demeter

Natalie Christine Giampietro

William Hunter Dent, Iii

Lindsey Gayle Fischer

Erich W Baum

Dalian Zhao

Zhonghua Zhang

Jeff Petkus

Patricia Andres

Zhiwei Cao

The present disclosure relates to: a) solid state forms of hydrobromide salts of Compound 1; b) pharmaceutical compositions comprising one or more solid state forms of hydrobromide salts of Compound 1, and, optionally, a pharmaceutically acceptable carrier; c) methods of treating tumors or cancers by administering one or more solid state forms of hydrobromide salts of Compound 1 to a subject in need thereof; and d) methods for the preparation of solid state forms of Compound 1.

Solid state forms of (S)-2-(((S)-6,8-difluoro-1,2,3,4-tetrahydronaphthalen-2-yl)amino)-N-(1-(2-methyl-1-(neopentylamino)propan-2-yl)-1H-imidazol-4-yl)pentanamide and uses thereof

The present invention relates to malate salt of a multi-tyrosine kinase inhibitor. In particular, the present invention relates to crystalline forms of the malate salt of multi-tyrosine kinase inhibitor N-(3-fluoro-4-((2-(5-(((2-methoxyethyl)amino)methyl)pyridin-2-yl)thieno[3,2-b]pyridin-7-yl)oxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide (S)-2-hydroxysuccinate (1:1), pharmaceutical compositions comprising the crystalline form, processes for preparing the crystalline form and methods of use therefore.

Crystalline salt of a multi-tyrosine kinase inhibitor, method of preparation, and use thereof

The present invention provides a malonate salt of a compound of formula (I): which is a crystalline salt. Also provided are pharmaceutical compositions that include the provided malonate salt and methods of using the provided crystalline forms and pharmaceutical compositions for the treatment of cancer.

[object Object]

This disclosure relates to the field of molecules having pesticidal utility against pests in Phyla Nematoda, Arthropoda, and/or Mollusca, processes to produce such molecules and intermediates used in such processes, compositions containing such molecules, and processes of using such molecules against such pests. These molecules may be used, for example, as nematicides, acaricides, insecticides, miticides, and/or molluscicides. This document discloses molecules having the following formula ('Formula One'). 

Molecules having certain pesticidal utilities, intermediates, compositions, and processes, related thereto

Pesticidal compositions and their uses are disclosed.

Pesticidal compositions

The present invention concerns novel heteroaryl-N-aryl thiosemicarbazones and their use in pest control, as insecticides and aca&#x3c0;cides This invention also includes preparation of the pesticide compositions containing the compounds, and methods of controlling insects using the compounds.

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Bloomington, IN, United States of America

Emily Marie Rigsbee