Waters Technologies Corporation

Emily J Berg

Joshua A Shreve

Joseph D Michienzi

Michael O Fogwill

James Usowicz

Douglas P Wittmer

Aaron Lebeau

Edwin H Denecke

Scott Kelley

James E Usowicz

The present technology generally relates to devices, systems and methods for providing robust sealing between surfaces in a pressurized system, such as a chromatography system. In particular, the devices, systems and methods relate to compliant and resilient parts that can be reused and/or reinstalled while providing a pressure tight sealing surface even within a high pressure environment (e.g., 1000 psi or greater).

Method and apparatus for high pressure sealing

The technology generally relates to tailoring a back pressure regulator in a chromatographic system to reduce unswept volume within the back pressure regulator to achieve better sample detection and a reduction in chromatographic band distortion effects.

Method and apparatus for minimizing the chromatographic band distortion of a back pressure regulator

Examples of gas liquid separators include a chamber, a fluid mixture inlet, a gas outlet and a liquid outlet. The fluid mixture inlet and the gas and liquid outlets are in fluid communication with the chamber. A fluid mixture received at the fluid mixture inlet diffuses inside the chamber and is separated into a liquid and a gas. The separated liquid is gravity-fed to the liquid outlet. The gas liquid separators have reduced dispersion and increased liquid recovery in comparison to conventional gas liquid separators used for chromatographic separations. The reduced dispersion yields an improvement in the shape of chromatographic peaks.

Gas liquid separator for chromatography applications

A supercritical fluid chromatography system is provided with an injection valve subsystem for introducing a sample into a flow of mobile phase fluid. The injection valve subsystem includes an auxiliary valve and an inject valve. The operations of the auxiliary and inject valves are coordinated in such a manner as to reduce sample carry-over and system pressure perturbations occurring during sample injection.

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Douglas, MA, United States of America

Emily J Berg