Dharmacon, Inc.

Ge Healthcare Dharmacon, Inc.

Thermo Fisher Scientific Biosciences Inc.

Emily Anderson

Anastasia Khvorova

Devin Leake

Christina Yamada

Rob Kaiser

Yuriy Fedorov

Michael O Delaney

Barbara Roberson

Provided herein are tripartite oligonucleotide complexes which can be administered to a cell, tissue or organism to silence a target gene. The tripartite oligonucleotide complexes of the disclosure may include a conjugate moiety that facilitates delivery to a cell, tissue or organism without the aid of a transfection reagent.

Tripartite oligonucleotide complexes and methods for gene silencing by RNA interference

Provided herein are duplex oligonucleotide complexes which can be administered to a cell, tissue or organism to silence a target gene without the aid of a transfection reagent(s). The duplex oligonucleotide complexes of the disclosure include a conjugate moiety that facilitates delivery to a cell, tissue or organism.

Duplex oligonucleotide complexes and methods for gene silencing by RNA interference

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Lafayette, CO, United States of America

Emily Anderson