Sanofi

Centre National De La Recherche Scientifique

Societe Anonyme Sanofi

Emilio Crisafulli

Paolo Carminati

Alberto Bianchetti

Dino Nisato

Gerard R Le Fur

Pierre Gros

Jean-Paul Kan

Michel Sabadie

Marco Frigerio

Guy Mazue

Michele Bousquet

Jeanine Etienne

Yannick C James

Alain Comment

The present invention relates to the use of ademetionine or one of its salts for the preparation of pharmaceutical or cosmetic compositions for counteracting ageing of the skin. It further relates to the said cosmetic compositions.

Composition and use of ademetionine against ageing of the skin

The invention relates to the 2-aminoalkyl-9-hydroxyellipticinium chloride hydrochloride of formula: ##STR1## in which Z represents hydrogen or a lower alkyl group, Alk represents a lower alkylene group and Am represents a di(lower alkyl)amino, pyrrolidino or piperidino group. These compounds are useful as antitumour agents.

Hydrochlorides of chlorides of 2-aminoalkyl-9-hydroxy-ellipticinium

A probe comprising a casing of which one face which will be in contact with the skin is providied with an aperture, is connected to a measuring device by means of a flexible connection in fiber optics comprising at least three optical conductors which, at a first end, are secured in the casing of the probe such as to face the aperture thereof, the first and second conductors having their first end portions directed respectively in a first and a second directions which are symmetrical to each other with respect to an axis extending normally through the aperture, while the third conductor has its first end portion directed in another direction than said second direction.

Skin reflectance measuring apparatus

The invention relates to 4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridines of formula ##STR1## in which R represents a cyano, acetyl or cycloalkyl group of from 3 to 7 carbon atoms and Alk represents a straight or branched alkylene of from 1 to 4 carbon atoms, as well as to the salts thereof, having an anorectic acitivity, to a process for preparing same and to pharmaceutical compositions containing said compounds, useful in the treatment of obesity.

Anorectic agent;

2-piperazinopyrimidine salt and pharmaceutical compositions containing it

The invention relates to 4-(-3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridines of formula ##STR1## in which R represents a cyano, acetyl or cycloalkyl group of from 3 to 7 carbon atoms and Alk represents a straight or branched alkylene of from 1 to 4 carbon atoms, as well as to the salts thereof, having an anorectic activity, to a process for preparing same and to pharmaceutical compositions containing said compounds, useful in the treatment of obesity.

Substituted trifluoromethylphenyltetrahydropyridines having a cyano

The invention relates to 4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridines of formula ##STR1## in which R represents a cyano, acetyl or cycloalkyl group of from 3 to 7 carbon atoms and Alk represents a straight or branched alkylene of from 1 to 4 carbon atoms, as well as to the salts thereof, having an anorectic activity, to a process for preparing same and to pharmaceutical compositions containing said compounds, useful in the treatment of obesity.

Substituted trifluoromethylphenyltetrahydropyridines having an anorectic

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Milan, Italy

Emilio Crisafulli