Catalent U.k. Swindon Zydis Limited

Emilie Masto

Rosaleen McLaughlin

Susan Gerrard Banbury

Yik Teng Wong

Lisa Garrett

Niamh Barrat

Disclosed herein is a solid lyophilized vaginal dosage form that can have an effective amount of at least one active ingredient, a crystalline structure forming agent in an amount of about 5 wt. % to about 40 wt. %, based on the total weight of the lyophilized dosage form, and at least one polymeric mucoadhesive matrix forming agent. The dosage form can have a pH of about 4.0 to 5.0, and can disintegrate within 120 seconds after being contacted with a vaginal mucosa. A method of delivering an active ingredient to the vaginal mucosa using the disclosed solid dosage form is also described.

Growing community of inventors

Swindon, United Kingdom

Emilie Masto