Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt.

Kozponti Valto-es Hitelbank Rt. Innovacioalap

Emil Minker

Dezso Korbonits

Gergely Heja

Gabor Kovacs

Sandor Virag

Pal Kiss

Gyula Sebestyen

Laszlo Tardos

Endre Palosi

Tamas Szuts

Katalin Marmarosi Nee Kellner

Gabor Horvath

Ida Szvoboda Nee Kanzel

Peter S Kormoczy

Vera Gergely

Csaba Gonczi

Maria Szomor Nee Wundele

Sandor Antus

Jeno Marton

Agnes Gottsegen

Judit Kun

Lehel Koch

Lajos Wolf

Lorand Debreczeni

Maria Szomor

Zoltan Vargai

Zsuzsanna Rozsa

Kalman Szendrei

Andrea Bolehovszky

The present invention relates to new compounds of Formula I ##STR1## and physiologically acceptable salts thereof wherein A and B stand for oxygen or --CH.sub.2 group with the proviso that if A stands for oxygen, then B stands for --CH.sub.2 group and R stands for hydrogen and, if A represents a --CH.sub.2 group, then B stands for oxygen, R stands for a --CH.sub.2 Q group wherein Q stands for hydrogen, and pyrrolidino, piperidino or morpholino and a process for the preparation thereof and pharmaceutical compositions containing as active ingredient a compound of the Formula (I) or a physiologically acceptable salt thereof.

Xanthine derivatives

The invention relates to new oxidiazole-alkyl-purine-derivatives of the Formula I ##STR1## and pharmaceutically acceptable salts thereof wherein A stands for C.sub.1-4 alkylene and

Oxadiazole-alkyl-purine derivatives useful as antitussive agents

Antitussive compounds of the formula I ##STR1## or physiologically acceptable acid addition salts thereof are disclosed, where A stands for straight or branched chain C.sub.1-5 alkylene or ##STR2## R.sub.1 stands for straight or branched chain C.sub.1-10 alkyl, halogenoalkyl, hydroxyalkyl, C.sub.5-6 cycloalkyl, vinyl, 2-ethoxyethyl, carbonylalkyl or aminoalkyl of the formula ##STR3## wherein R stands for hydrogen or methyl, n is 0 to 3,

Theophyllinyl-alkyl-oxadiazoles, process for the preparation thereof and

A polysaccharide-concentrate obtained from plant of the genera Cucurbitaceae, Papilionaceae, Tiliaceae, Labiate, Malvaceae, Asteraceae, Umbelliferae, Rutaceae, Chenopodiaceae, Linaceae, Rosaceae and Plantaginaceae by extraction with water and precipitation of the polysaccharide with alcohol or acetone, if desired after further purification. The polysaccharides having a molecular weight between 75,000-2,000,000, containing maximum 5% of nitrogen, maximum 5% of phosphorus (expressed in P.sub.2 O.sub.5), maximum 25% of ash, minimum 30% of reducing sugar, minimum 60% of total sugar (after acidic hydrolysis, expressed as glucose) has been shown to have especially anti-inflammatory activity.

Biologically active polysaccharide concentrates and process for

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Szeged, Hungary

Emil Minker