Biomerieux, Inc.

Biomerieux Sa

Emiel Gerebern Maria Verwimp

Hermanus Johannes Maria Kreuwel

Bernardus Jozef Maria Beerling

Hermannus Johannes Maria Kreuwel

Franciscus Gerardus Spee

Patrick Broyer

Michel Guy

Massimo Galdiero

Emiliano Maione

Agnes Dupontfilliard

Agnès Dupontfilliard

A cartridge that can be positioned inside an air collection component and receive a component for recovering nucleic acids is described, the cartridge being substantially cylindrical and containing a microorganism retaining zone, the retaining zone containing a microorganism lysis mechanism. Also described is a device for collecting microorganisms contained in the air and a device for microorganism lysis.

Device for the lysis of microorganisms present in an environmental or clinical sample and the extraction of nucleic acids from said microorganisms for analysis

The present invention relates to, among other things, a device for collecting airborne microorganisms, said device having:

Automated system for the lysis of microorganisms present in a sample, for extraction and for purification of the nucleic acids of said microorganisms for purposes of analysis

The present invention is related to devices for manipulating magnetic particles that are suspended in a fluid, possibly containing a biological entity of interest, the magnetic particles being able to bind the entity of interest, the fluid being contained in a reaction vessel constituted by a large upper compartment with a funnel shape, an elongate lower compartment with a substantially constant cross-section and a closed base. The devices are especially useful in methods for the extraction of nucleic acid to enable them for further processing.

Devices for separating, mixing and concentrating magnetic particles with a fluid

A process for manipulating magnetic particles suspended in a fluid that are able to bind to an entity of interest, the fluid being contained in a reaction vessel having a large funnel shaped upper compartment, an elongate lower compartment of substantially constant cross-section and a closed base. The process consists of:

Device and method for separating, mixing and concentrating magnetic particles with a fluid and use thereof in purification methods

This invention relates to the use of magnetic or magnetizable particles, and, in particular, to methods of mixing magnetic or (super)paramagnetic particles efficiently with a fluid and the separation of the magnetic particles from a fluid, optionally followed by resuspension of the particles in another fluid. The present invention provides a method of mixing, in one or more container(s), magnetic or (super)paramagnetic particles with a fluid, using more than one magnets, whereby the containers are subjected to magnetic fields with different and changing directions by moving the magnets with respect to the position of the container(s) and/or by moving the containers with respect to the positions of the magnets. The invention further provided a device for doing the same. Preferably the holders for the containers and the magnets in the device are placed in intervening array geometrics and the magnets are placed in line in such a way that all magnets that are in line have their poles oriented in the same direction, and that all magnets in a neighboring line have their poles oriented in the reverse direction with respect to the poles of the magnets in the first line.

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Kasterlee, Belgium

Emiel Gerebern Maria Verwimp