McMaster University

Societe De Commercialisation Des Produits De La Recherche Appliquee Socpra Sciences Et Genie S.e.c.

Emanuel Escher

Ashok K Grover

Jyoti Chaudhary

Ximing Ding

Jan J Dubowski

Eric H Frost

A method and a device for detecting the presence of a predetermined substance, in which a quantum dot is produced on a substrate. The quantum dot emits a radiation at a predetermined wavelength, and is covered with a surface layer to which the predetermined substance attaches. A deviation of the value of a parameter related to the radiation is produced when the predetermined substance attaches to the surface layer. This deviation can be detected to thereby sense the presence of the predetermined substance.

Quantum dot template for fast and simultaneous detection of different infectious agents

Novel compound called caloxins which are extracellular plasma membrane (PM) Ca-pump inhibitors are described. One caloxin is caloxin 2A1 and has the amino acid sequence VSNSNWPSFPSSGGG. Another caloxin is caloxin 3A1 and has the amino acid sequence DSHINNEPSRRRGGGK. The caloxins are useful in inhibiting PM Ca-pumps and can be used in the development of treatments of various diseases including hypertension, hypotension, degenerative brain disorders, mood disorders, diabetes, kidney failure and cancer.

Caloxins

Growing community of inventors

Sherbrooke, Canada

Emanuel Escher