Ninepoint Medical, Inc.

The General Hospital Corporation

Namati, Eman

Sinclair, Matthew A.

Al-qaisi, Muhammed

Vader, David

Graf, Benedikt

Eman Namati

Benedikt Graf

David Vader

Matthew A Sinclair

Muhammad Al-Qaisi

Michael Madden

James W Moriarty, Jr

J Christopher Flaherty

Guillermo J Tearney

Brett Eugene Bouma

Eric A Swanson

Ben Graf

Tsung-Han Tsai

Brian G Connor

Paul Neumann

Ben Vakoc

Jonathan Lawrence Goodwin

Matthew A Siclair

Muhammed Al-Qaisi

James W Moriarity

Nilma Shokrollahi

James Houskeeper

Marshall Houskeeper

Kenneth O'BRIEN

The present disclosure provides an OCT imaging system to reduce or eliminate frequency-domain aliasing artifacts. The frequency is shifted using a carrier frequency to define a sampling range substantially centered on the carrier frequency. An image of the sample is generated from a displayed imaging range that consists of a subset of the frequencies within the sampling range. Furthermore, the system may be configured to determine the carrier frequency such that a Nyquist frequency corresponding to the shifted frequency is extended beyond either an upper or a lower bound of an OCT quality envelope corresponding to the first portion of light. Additionally, the carrier frequency may be determined such that a lower bound of the OCT quality envelope is greater or less than a zero-frequency DC limit.

Frequency-domain optical coherence tomography with extended field-of-view and reduction of aliasing artifacts

An exemplary capsule apparatus is provided, which includes a capsule having a first end and a second end opposite to the first end. A terminal portion of the capsule at the first end has a tapered end that has a section which curves toward a center of the terminal portion. Additionally, a tethered capsule apparatus includes a capsule configured to provide imaging optics having an orifice provided at least one end thereof. A tether having a proximal end and a distal end is also be provided. The distal end of the tether has an enlarged end portion that has a width that is greater than a width of a neighboring portion, and the enlarged end portion can be positioned and configured to be secured in the orifice.

Enclosed imaging apparatus and method for use thereof

The present disclosure provides an OCT imaging system having a variety of advantages. In particular, the OCT system of the present disclosure may provide a more intuitive interface, more efficient usage of controls, and a greater ability to view OCT imaging data.

Determining angular orientation for imaging

Systems, devices and methods for producing registered images of a body lumen are provided. The system includes a first imaging device having an imager positioned at a distal end thereof, said first imaging device configured to produce a first image of a body cavity; and an imaging system, including a second imaging device having an imager positioned at a distal end thereof and configured to be positioned approximate to said imager of said first imaging device within said body cavity and configured to produce a second image; an elongated member configured to contain said second imaging device; and at least one marker configured to produce registration information in the first image and the second image.

Imaging system producing multiple registered images of a body lumen

Angular image manipulation

Exemplary apparatus and method can be availed for providing at least one electromagnetic radiation. For example, it is possible to provide at least one first electromagnetic radiation having a frequency that changes over time with a first characteristic period. Further, with at least one hardware arrangement, it is possible to receive and modify the first electromagnetic radiation(s) into at least one second electromagnetic radiation having a frequency that changes over time with a second characteristic period. The second characteristic period can be smaller than the first characteristic period. The hardware arrangement(s) can include a resonant cavity having a round-trip propagation time for the first electromagnetic radiation(s) that can be approximately the same as the first characteristic period.

Apparatus and methods for producing and/or providing recirculating optical delay(s)

Systems, devices and methods of producing an image are provided. A electro-magnetic radiation source provides electro-magnetic radiation to a sample and a reference. A detector/interferogram unit produces at least one interferogram that is supplied to a signal processing unit. The signal processing unit extracts phase, magnitude, and/or polarization data from the supplied signals, and produces an image based on at least the extracted data.

Systems and methods for signal processing in optical imaging systems

Growing community of inventors

Belmont, MA, United States of America

Eman Namati