Brainscope Company, Inc.

Everest Biomedical Instruments Company

Capnia, Incorporated

Ocean Tomo, LLC

Everest Biomedical Instruments

Stryker Corporation

Washington University

Skullcandy, Inc.

New York University

Elvir Causevic

Eldar Causevic

Martin Rathgeber

Lee R Carlson

Craig Anderson

Joe Martinosky

Daniel Metzger

Edward A McClatchie

Ralph Walden

Richard Comrie Watt

Gregory James Holderfield

Greg Holderfield

Mladen Victor Wickerhauser

Anthony D Wondka

Neil Samuel Rothman

Leslie S Prichep

Arthur H Combs

Christian Christiansen

Matthew Beers

Arnaud Eric Jacquin

Thomas C Burton

Matthew Windt

Thomas Bishop

Anish Bhatnagar

Elliott Hsu

Randall Jeffrey Krohn

Emily Cook

Samuel Noertiker

Ines Kusturica

Kristopher C Fike

Samuel R Paschel, Jr

S Hoby Darling

Elliot Hsu

Arnaud Jacquin

A machine-learning based artificial intelligence device for finding an estimate of patent quality, such as patent lifetime or term is disclosed. Such a device may receive a first set of patent data and generate a list of binary classifiers. A candidate set of binary classifiers may be selected and using a heuristic search, for example an artificial neural network (ANN), a genetic algorithm, a final set of binary classifiers is found by maximizing iteratively a yield according to a cost function, such an area under a curve (AUC) of a receiver operating characteristic (ROC). The device may then receive patent information for a target patent and report an estimate of patent quality according to the final set of binary classifiers.

Machine learning-based patent quality metric

Methods and systems are described to obtain and analyze one or more gas samples from the breath of a person, and organizing the samples in a sample registry for subsequent analysis. This technique solves the various problems that are associated with targeting an individual breath for analysis, and allows for additional versatility and options in the analysis process.

Sampling and storage registry device for breath gas analysis

Presented are systems and methods that analyze an individual's state based on selected criteria, and then adaptively provide stimuli to affect the individual's performance compared to established benchmarks and pre-set plans. The methods or systems can provide audio and/or tactile inputs to a human subject to obtain a specific performance state. A music or sound selection engine considers the sensory and environmental inputs and selects the appropriate music or auditory stimulus, with the intent to reach a desired state of flow. The methods and systems can employ multiple measurements of personal data that can correlate to the emotional state of a subject. By manipulating stimuli delivered to an individual, ultimate performance can be improved over various planning horizons.

Human performance optimization and training methods and systems

An improved apparatus and method for capturing and analyzing the end-tidal portion of an exhalation. The COlevel of air drawn into the system () is monitored to distinguish inhalation and exhalation of breath. Upon detection of a decrease in the COlevel in the air drawn into the system (), indicating a transition between exhalation and inhalation a pair of flow selector valves () are operated to capture the end-tidal volume of air drawn into the system () immediately prior to the detection of the decrease in the COlevel. Incoming air is diverted around the captured volume of air, and the COlevels are continually monitored to ensure that the captured volume of air corresponds to the end-tidal portion of an exhalation. Once the captured volume of air is positively identified as the end-tidal portion of an exhalation, the captured volume is routed through a gas analyzer () for analysis of one or more predetermined gas levels.

Breath end-tidal gas monitor

A method and apparatus for providing an on-site diagnosis of a subject to determine the presence and/or severity of a concussion is provided. The method includes placing an electrode set coupled to a handheld base unit on the subject's head, acquiring brain electrical signals from the subject through the electrode set, processing the acquired brain electrical signals using a signal processing algorithm stored in a memory of the base unit, determining the presence and/or severity of a concussion from the processed signals, indicating the presence and/or severity of a concussion on the handheld base unit, and determining a course of treatment for the subject based on the indication.

Field-deployable concussion detector

A method and apparatus for performing rapid brain assessment may provide emergency triage to head trauma patients by analyzing a combination of spontaneous and evoked brain potentials. The spontaneous and evoked potentials are analyzed, and the results classified, to present a real-time assessment of a patient's brain, diagnosing any potential abnormalities therein.

Portable automatic brain state assessment apparatus

A method and apparatus for utilizing the benefits of encoded signal transmission and reception to enhance the performance of medical testing devices () adapted to evoke and measure biological response signals such as auditory evoked potentials (AEP), and the auditory brainstem response (ABR) signals in particular. Auditory stimuli, such as clicks, are presented to the ear of a human patient, in a predetermined encoded sequence, resulting in the generation of auditory responses and bio-electric response signals in the human patient. These response signals from the patient are acquired and observed, and are processed according to the predetermined encoded sequence in which the auditory stimuli were presented to the patient's ear in order to extract the desired auditory evoked potential signals or ABR signals.

Method and apparatus for signal encoding evoked responses

Systems and methods for assessing a patient's neurologic state based on auditory evoked responses are provided.

Method and apparatus for automatic evoked potentials assessment

A system for delivering health information is provided. The system comprises at least one apparatus configured to receive information related to a condition of a patient. The analysis system further comprises a reception system configured to receive data related to the patient's condition and a processor configured to assess a condition of a patient and to identify a data set including information related to the patient's condition. The system also comprises a communication system configured to communicate the data set to a user.

System and methods for management of disease over time

Methods and systems for assessing brain activity and collecting information related to a patient's condition and brain electrical activity are provided.

System and methods for neurologic monitoring and improving classification and treatment of neurologic states

A headset for detecting brain electrical activity is disclosed. The headset may have a flexible band having a first end and a second end. The flexible band may have at least one expansible region permitting a distance between the first end and the second end to selectably vary. The headset may also have flexible circuitry in the flexible band. The flexible circuitry may be operatively connected to at least one sensor configured to sense brain electrical activity. The headset may further have a stimulus emitter coupled to the flexible band.

Flexible headset for sensing brain electrical activity

A disposable electrode arrayincluding a flexible memberin which a plurality of electrodesare disposed, having a shape adapted to contact the forehead skin surface on a human patient. A pair of ear loopscoupled to the disposable electrode arraysecure the disposable electrode arrayabout the patient's ears, with the flexible memberdisposed across the patient's bow, retaining the electrodesagainst the skin surface. Additional electrodesare disposed in proximity to the ear loopsand are configured to contact the skin surface behind the patient's ears. An auditory stimulus delivery elementis coupled with each of the ear loops, and positioned to seat in proximity to the patient's ear canal for the delivery of auditory stimulus. Electrical conductors associated with the electrodesand the stimulus delivery elementsare routed within the flexible memberto a common external connection pointfor connection to an external system. The disposable electrode arraymay be configured for both evoking and measuring evoked bio-potentials in the human subject, or for measuring bio-potentials evoked using a separate stimulus delivery system.

Electrode array

A method and apparatus for providing objective assessment of the brain state of a subject using a field portable device. The method includes placing an electrode set coupled to a handheld base unit on the subject's head, acquiring electrical brain signals from the subject through the electrode set, processing the acquired electrical brain signals using a feature extraction algorithm, classifying the extracted features into brain states, computing brain abnormality indices reflecting the probability of correct classification of brain state, and graphically displaying the classification result and the abnormality indices on the handheld base unit.

Method and device for probabilistic objective assessment of brain function

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San Francisco, CA, United States of America

Elvir Causevic