The United States of America, As Represented by the Secretary, Department of Health and Human Services

University of Kansas

Elma Aflaki

Wei Ping Zheng

Juan Jose Marugan

Noel Terrence Southall

Frank John Schoenen

Steven Andrew Rogers

Samarjit Patnaik

Wendy Westbroek

Ehud Goldin

Ellen Sidransky

Compounds of Formula (I) and the pharmaceutically acceptable salts thereof are disclosed. The variables. R-R, m, n, o, and p are disclosed herein. The compounds are useful for treating Gaucher disease and inhibiting the onset of Gaucher disease symptoms in a patient having a GBA gene mutation and for treating Parkinson's disease. Pharmaceutical compositions containing compounds of Formula (I) and methods of treatment comprising administering compounds of Formula (I) are also disclosed. 

Salicylic acid derivatives useful as glucocerebrosidase activators

Growing community of inventors

Rockville, MD, United States of America

Elma Aflaki