Dana-farber-cancer Institute Inc.

Ellen Weisberg

Nathanael Schiander Gray

Hwan Geun Choi

Jae Won Chang

Wenjun Zhou

Taebo Sim

Jianming Zhang

Sara Jean Buhrlage

James Douglas Griffin

The present invention is based, in part, on the identification of novel USP10 biomarkers and modulators, and methods of use thereof, for identifying, assessing, preventing, and treating AML.

Compositions and methods for identification, assessment, prevention, and treatment of AML using USP10 biomarkers and modulators

The present application relates to therapeutic organic compounds, compositions comprising an effective amount of a therapeutic organic compound; and methods for treating and preventing disease comprising administering and effective amount of a therapeutic organic compound to a subject in need thereof.

Fused 2-aminothiazole compounds

The present application relates to therapeutic organic compounds of formula (I), wherein Q, R1, R2, R3, and R4 are defined herein. The invention also relates to pharmaceutical compositions comprising an effective amount of a therapeutic organic compound; and methods for treating and preventing disease such as cancer comprising administering and effective amount of a therapeutic organic compound to a subject in need thereof.

Growing community of inventors

Nashua, NH, United States of America

Ellen Weisberg