Upm-kymmene Corporation

Elle Koivunotko

Markus Nuopponen

Marjo Yliperttula

Lauri Paasonen

Arto Merivaara

Anne Meriluoto

Sami Valkonen

Ossi Korhonen

Jacopo Zini

Lisa Chinello

Giulia Scapin

Kalle Manninen

A method for freeze-drying a hydrogel composition is disclosed, the method comprising providing the hydrogel composition, wherein the hydrogel composition comprises cellulose nanofibrils and/or cellulose nanocrystals, at least one saccharide, at least one amino acid, and biologics; and freeze-drying the hydrogel composition, thereby obtaining a freeze-dried hydrogel composition.

Method for freeze-drying a hydrogel composition and a freeze-dried hydrogel composition

The present disclosure relates to a method for controlling freeze-drying of a hydrogel wherein the method comprises adjusting the residual water content of the freeze-dried hydrogel, and to a freeze-dried hydrogel composition comprising nanoscale cellulose and a at least one biomolecule selected from an oligosaccharide or a disaccharide. The present disclosure further concerns the use of the freeze-dried hydrogel composition for cell culturing, a cell culturing scaffold as well as a process for manufacturing a reconstituted hydrogel.

Controlling freeze-drying of a hydrogel

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Helsinki, Finland

Elle Koivunotko