Aviva Biosciences Corporation

Elizabeth Kwok

Jing Cheng

Xiaobo Wang

Lei Wu

Junquan Xu

George T Walker

Mingxian Huang

Guoliang Tao

Douglas T Yamanishi

Jia Xu

Joe Ouyang

Paul G Hujsak

Ping Lin

Sara F Snyder

Charina Schmitigal

The present invention recognizes that diagnosis and prognosis of many conditions can depend on the enrichment of rare cells, especially tumor cells, from a complex fluid sample such as a blood sample. In particular, the present invention is directed to methods and compositions for detecting a non-hematopoietic cell, e.g., a non-hematopoietic tumor cell, in a blood sample via, inter alia, removing red blood cells (RBCs) from a blood sample using a non-centrifugation procedure, removing white blood cells (WBCs) from said blood sample to enrich a non-hematopoietic cell, if any, from said blood sample; and assessing the presence, absence and/or amount of said enriched non-hematopoietic cell.

Methods and compositions for detecting non-hematopoietic cells from a blood sample

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San Diego, CA, United States of America

Elizabeth Kwok