University System of Maryland

Becton Dickinson and Company Limited

Elisabeth Lily Sooklal

Dwight Livingston

Ammon David Lentz

Gary F Hershner

Joseph Kelleher

Sharon Virginia LaMont Leitch

Daniel Justin Lohan

Christopher M Jewell

James I Andorko

Stuart Martin

Rebecca Whipple Bettes

Kristi Chakrabarti

A pierceable cap may be used for containing sample specimens. The pierceable cap may prevent escape of sample specimens before transfer with a transfer device. The pierceable cap may fit over a vessel. An access port in the shell of the pierceable cap may allow passage of a transfer device through the pierceable cap. The shell receives a septum that has four half dome indentations, each indentation defining a quadrant of the septum interior. The indentations are separated by the septum floor which extends along respective first and second diameters of the septum and intersect at approximately ninety degrees. The half dome indentations guide a transfer device to the partially slitted portion of the septum floor.

Reclosing septum cap for medical sample transport and processing

The present invention provides a method for imaging microtentacles on isolated, living, non-adherent primary tumor cells from a cancer subject comprising: i) obtaining one or more living, non-adherent primary tumor cells that has been isolated from a solid tumor from the subject; and ii) imaging the one or more living, non-adherent primary tumor cells and detecting the microtentacles.

Microtentacle imaging in patient tumor samples

The present invention provides a device for assaying living cells comprising a substrate, wherein the substrate comprises one or more tethering molecules which adhere to the substrate and are capable of interacting with cell membranes of the cells, wherein the cells maintain a free-floating, non-adherent character when bound to the one or more tethering molecules.

Materials and methods for assaying living cells

Combined cap and septum assembly for a vessel

Septum for a vessel

Growing community of inventors

Reisterstown, MD, United States of America

Elisabeth Lily Sooklal