Pierre Fabre Medicament

R.p.scherer Technologies, Inc.

Pierre Fabre Dermatologie

Elie Leverd

Marie-Dominique Ibarra

Marie-Madeleine Bohn

Norbert Heintz

Joël Bougaret

Peter Van Hoogevest

Eric Goutay

Jo&euml;l Bougaret

Monique Seiller

Jean-Louis Grossiord

Serge Basquin

Joël Bougáret

Alexandre Gil

Mathew Leigh

Pascal Lombardin

Elsa Kung

Michel Bauer

Valérie Muguet

Christine Chaumont

This invention relates to solid and stable dispersions of a hydrosoluble derivative of vinca alkaloids in at least one polyethyleneglycol with a molecular mass between 800 and 30 000.

Stable solid dispersion of a derivative of vinca alkaloid and process for manufacturing it

The present invention relates to a pharmaceutical composition to be parenterally administered, including submicronic ester particles of docosahexaenoic acid, dispersed in an aqueous phase using a mixture of at least two surfactants selected from among a) at least one polyoxyethylene fatty acid ester and b) at least one phospholipid derivative. The present invention also relates to the method for preparing said pharmaceutical composition.

Pharmaceutical composition including a DHA ester to be administered parenterally

This invention relates to pharmaceutical compositions consisting of a semisynthetic derivative of vinca alkaloid, stable at room temperature, in which said derivative is present in the form of a freeze dried product obtained in the presence of at least one carbohydrate.

Freeze-dried injectable pharmaceutical combination of semisynthetic vinca alkaloids and carbohydrate stable at room temperature

The invention described herein relates to a pharmaceutical composition containing vinorelbine as an active ingredient which is suitable for encapsulation in soft capsules. The liquid oral pharmaceutical composition suitable for a liquid fill composition for a soft capsule dosage form comprises: vinorelbine or a pharmaceutically acceptable salt thereof; ethanol; water; glycerol; and polyethylene glycol. In a preferred embodiment, the tartrate salt form of vinorelbine is used in the composition. The invention also provides for a method of treating cancer comprising orally administering, to a patient in need of treatment thereof, a soft capsule comprising the pharmaceutical composition of the invention.

Oral pharmaceutical composition for soft capsules containing vinorelbine and method of treatment

The invention concerns more particularly dodecylthio-phenylacetanilide derivative complexes such as (S)-2',3&#x2032;,5&#x2032;-trimethyl-4&#x2032;-hydroxy-&#x3b1;-dodecylthio-phenylacetanilide or related derivatives thereof and cyclodextrins.

Anilide and cyclodextrin complexes, their preparation and their use as medicine in particular for treating dyslipidemiae

The invention concerns liquid or pasty thixotropic compositions containing an active substance for filling capsules at room temperature. The compositions become fluid by the effect of shearing when they pass through the filling nozzle, then recover their consistency with sufficient intensity and rapidity to prevent, after filling any leak between the two capsule parts. Said compositions are characterized in that their rheological properties are specially adapted for filling and for optimal recovery of consistency. They are preferably in the form of dispersions supporting amphiphilic excipients. Said compositions enable the formulation of active liquid, pasty and even solid substances.

Thixotropic formulations for filling capsules

The invention relates to a stable aqueous solution of vincristine sulfate comprising:

Stable aqueous solution of vincristine sulfate

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Castres, France

Elie Leverd