Alza Corporation

Henkel Ag & Company, Kgaa

Eli J Goldman

Paul B Foreman

Jianye Wen

Eric N Silverberg

Allison Luciano

Robert M Gale

Jay Douglas Audett

Jay Audette

Lothar W Kleiner

Stephanus Pudjijanto

Subramanian S Venkatraman

A polyacrylate formulation suitable for delivery of drug to through a body surface of an individual. By loading the drug and permeation enhancers at a high concentration into a polyacrylate proadhesive that has inadequate adhesive properties for typical adhesive application on the skin, a formulation with desirable adhesive characteristics and effective therapeutic properties can be made. The proadhesive has higher glass transition temperature than typical pressure sensitive adhesives.

High enhancer-loading polyacrylate formulation for transdermal applications

Method of making a high enhancer-loading polyacrylate formulation for transdermal applications

A polyacrylate formulation suitable for delivery of drug through a body surface of an individual. By loading the drug and permeation enhancers at a high concentration into a polyacrylate proadhesive that has inadequate adhesive properties for typical adhesive application on the skin, a formulation with desirable adhesive characteristics and effective therapeutic properties can be made. The proadhesive has higher glass transition temperature than typical pressure sensitive adhesives.

Acrylic polymers comprising vinyl acetate monomers, hydroxyl functional monomers and low Tg alkyl acrylate monomers are useful in adhesive compositions that find use in skin contact applications.

Acrylic polymer-based adhesives

Acrylic polymers comprising a non-primary hydroxyl functional monomer and low Tg alkyl acrylate monomers are useful in adhesive compositions that find use in skin contact applications.

The present invention relates to hydratable drug reservoir films for electrotransport drug delivery devices and to electrotransport drug delivery systems containing the hydratable drug reservoirs and to methods for manufacturing and using such systems. The hydratable reservoir films according to this invention are easily manufacturable and rapidly imbibe water and/or drug solution with good water retention and stability.

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San Francisco, CA, United States of America

Eli J Goldman