Aarhus Universitet

Elena Simona Radutoiu

Jens Stougaard Jensen

Lene Heegaard Madsen

Kasper Røjkjær Andersen

Zoltan Bozsoki

Simon Boje Hansen

Kira Gysel

Niels Nørgaard Sandal

Aspects of the present disclosure relates to genetically altered LysM receptors. In particular, the present disclosure relates to a hydrophobic patch into the LysM2 domain which can increase affinity and/or selectivity for LCOs and by replacement of regions in the LysM1 domain with the corresponding regions of the LysM1 domain from a donor LysM receptor that can alter the affinity and/or selectivity for the oligosaccharide particularly for LCOs and can alter the specificity between LCO when using regions from a high affinity and specificity LCO LysM receptor such as a legume NFR1 receptor. The present disclosure also relates to genetically altering LysM receptors in plants to include a hydrophobic patch or alter the hydrophobic patch and to genetically altering LysM receptors in plants by replacement of regions in the LysM2 domain.

Genetically altered LysM receptors with altered agonist specificity and affinity

Growing community of inventors

Aarhus, Denmark

Elena Simona Radutoiu