Mcneil-ppc, Inc.

Eleanor M Freeman

Edward J Roche

Susan M Papile

Susan Decoteau

A solid oral dosage form for the treatment of gastrointestinal disorders comprising a therapeutically effective amount of a therapeutically effective amount of guanidinothiazole compound; and a therapeutically effective amount of an antacid wherein the pharmaceutical and an antacid are separated by a barrier which is substantially impermeable to an antacid.

Pharmaceutical compositions containing famotidine and aluminum hydroxide

Chewable medicament tablets are made from coated rotogranules of a medicament wherein the rotogranules are formed from a granulation mixture of: medicament, e.g. famotidine; binder, e.g. HPMC; and carrier, e.g. lactose; and the rotogranules are coated with cellulose acetate, cellulose acetate butyrate or a combination thereof and hydroxypropyl cellulose. A process for making such tablets and a method of providing taste masking of medicaments utilizing such coated rotogranules.

Taste mask coatings for preparing chewable pharmaceutical tablets

Chewable medicament tablets are made from coated rotogranules of a medicament wherein the rotogranules are formed from a granulation mixture of medicament, e.g. famotidine binder, e.g. polyvinylpyrrolidone, and carrier, e.g. lactose and the rotogranules are coated with cellulose acetate, cellulose acetate butyrate or a combination thereof and polyvinyl pyrrolidone and a process for making such tablets and a method of providing taste masking of medicaments utilizing such coated rotogranules.

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Norristown, PA, United States of America

Eleanor M Freeman