Agensys, Inc.

Elana Levin

Aya Jakobovits

Rene S Hubert

Pia M Challita-Eid

Daniel E H Afar

Arthur B Raitano

Mary Faris

Steve Chappell Mitchell

Karen Jane Meyrick Morrison

Daniel E Afar

Daniel EH Afar

A novel gene (designated 84P2A9) and its encoded protein is described. While 84P2A9 exhibits prostate and testis specific expression in normal adult tissue, it is aberrantly expressed multiple cancers including prostate, testis, kidney, brain, bone, skin, ovarian, breast, pancreas, colon, lymphocytic and lung cancers. Consequently, 84P2A9 provides a diagnostic and/or therapeutic target for cancers, and the 84P2A9 gene or fragment thereof, or its encoded protein or a fragment thereof used to elicit an immune response.

84P2A9: a prostate and testis specific protein highly expressed in prostate cancer

A novel gene (designated 108P5H8) and its encoded protein, and variants thereof, are described wherein 108P5H8 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, 108P5H8 provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 108P5H8 gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with 191P1E1B can be used in active or passive immunization.

Method of inhibiting growth or survival of a cell by providing an anti-108P5H8 antibody

Antibody that binds zinc transporter protein 108P5H8

A novel gene (designated 158P1D7) and its encoded protein are described. While 158P1D7 exhibits tissue specific expression in normal adult tissue, it is aberrantly expressed in multiple cancers including set forth in Table 1. Consequently, 158P1D7 provides a diagnostic and/or therapeutic target for cancers. The 158P1D7 gene or fragment thereof, or its encoded protein or a fragment thereof, can be used to elicit an immune response.

Nucleic acid and corresponding protein named 158P1D7 useful in the treatment and detection of bladder and other cancers

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Los Angeles, CA, United States of America

Elana Levin