The General Hospital Corporation

Marvelbiome, Inc.

Elamparithi Jayamani

Jothi Amaranath Govindan

Gary B Ruvkun

Priti H Chatter

J Amaranath Govindan

Mukesh Chatter

Gary Ruvkun

Provided herein are methods and compositions comprising a bacterium or a metabolite thereof for enhancing mitochondrial and/or peroxisomal function.

Compositions and methods for improving mitochondrial function

Methods and uses of compositions (e.g. comprising one or more microbial strains, one or more components, one or more metabolites, or a combination thereof) for treating neurodegenerative diseases, disorders, and conditions are disclosed.

Methods and uses of microbiome compositions, components, or metabolites for treating neurodegenerative diseases

A system is provided comprising a plurality ofcultures, where each culture comprises a transgenicstrain that models a mammalian disease or condition. Methods of using a system, e.g., for characterizing microbial strains of a mammalian microbiome and determining whether such microbial strains affect a mammalian disease or disorder.

Compositions and methods for characterizing a microbiome

A combination is provided comprising an ellagitannin composition, and an enzymatic composition comprising one or more ellagitannin enzymes, where the one or more ellagitannin enzymes comprise a tannin acyl hydrolase enzyme, a gallate decarboxylase enzyme, or a combination thereof. Methods of making and using combinations disclosed herein are also provided.

Microbial compositions comprising ellagitannin and methods of use

Methods and compositions comprising carotenoids for the treatment or prevention of nausea, e.g., chemotherapy-induced nausea and vomiting.

Growing community of inventors

Malden, MA, United States of America

Elamparithi Jayamani