Pfizer Corporation

Other

Elaine V Jones

Timothy J Miller

Albert Paul Reed

Sharon R Klepfer

Ganesh Madhusudan Sathe

Michael Thomas Clark

Hector Wasunna Alila

Shawn Patrick O'Brien

Brian T Suiter

Nancy E Pfeiffer

Mark William Mellencamp

The present invention relates to polypeptides and proteins useful in the diagnosis and prevention of disease caused by feline infectious peritonitis virus (FIPV) and feline enteric coronavirus (FECV).

Recombinant feline coronavirus S proteins

The present invention provides the amino acid and nucleotide sequences of a CCV spike gene, and compositions containing one or more fragments of the spike gene and encoded polypeptide for prophylaxis, diagnostic purposes and treatment of CCV infections.

Canine coronavirus S gene and uses therefor

This invention relates to immunogenic compositions capable of potentiality growth hormone activity, comprising an immunologically effective amount of a composite peptide comprising at least two non-contiguous somatotropin epitope amino acid sequences, wherein said composite peptide is substantially free of receptor binding domain sequences; and an immunologically acceptable excipient. The invention further relates to methods of using an immunogenic composition of the invention to potentiate the action of growth hormone in pigs.

Immunogenic compositions that potentiate growth hormone activity

The present invention provides polynucleotide molecules encoding portions of the S protein from feline infectious peritonitis virus (FIPV). The present invention further provides polynucleotide molecules encoding the entire S protein or portions thereof from feline enteric coronavirus (FECV). The polynucleotide molecules of the present invention are useful as diagnostic reagents.

This invention relates to composite somatotropin peptides comprising somatotropin epitopic amino acid sequences, and fusion proteins thereof, useful in potentiating growth hormone activity. Also disclosed are vectors and host cells useful in the recombinant production of such molecules. Vaccines containing the composite somatotropin peptides and fusion proteins of the present invention, and methods of using the same, are disclosed.

Fused somatotropin epitopic peptides that potentiate growth hormone

This invention relates to composite somatotropin peptides and fusion protein thereof useful in the potentiating of growth hormone activity. Also disclosed are vector and host cells useful in the recombinant production of such molecules. Vaccines containing composite somatotropin and fusion proteins thereof and methods of using same as disclosed.

Fused proteins

A method of preparation of a vaccine for use in immunizing animals against pseudorabies virus (PRV) infection which comprises inactivated recombinant PRV subunit antigens. Also described is a diagnostic kit for detection of PRV infection which distinguishes vaccinated animals from naturally exposed animals.

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Wynnewood, PA, United States of America

Elaine V Jones