Ajinomoto Co., Ltd.

Ekaterina Aleksandrovna Slivinskaya

Yury Ivanovich Kozlov

Konstantin Vyacheslavovich Rybak

Yoshihiko Hara

Hisashi Yasueda

Elvira Borisovna Voroshilova

Hiroshi Izui

Joanna Yosifovna Katashkina

Akito Chinen

Mikhail Markovich Gusyatiner

Takuji Ueda

Tatyana Viktorovna Leonova

Vera Georgievna Doroshenko

Sergei Vladimirovich Mashko

Tomoko Suzuki

Aleksandra Yurievna Skorokhodova

Elena Vitalievna Klyachko

Ekaterina Alekseevna Savrasova

Larisa Gotlibovna Airikh

Valeriy Zavenovich Akhverdian

Vitaly Grigorievich Paraskevov, Legal Representative

Marina Evgenievna Sheremet'eva

Yulia Aleksandrovna Ovodova

Tomoko c/o Ajinomoto Co Inc Suzuki

Hisashi Ajinomoto Co Inc Yasueda

Yoshihiko Ajinomoto Co Inc Hara

Akito Ajinomoto Co Inc Chinen

Hiroshi Ajinomoto Co Inc Izui

The present invention provides a bacterium which has an ability to produce a useful metabolite derived from acetyl-coenzyme A, such as L-glutamic acid, L-glutamine, L-proline, L-arginine, L-leucine, L-cysteine, succinate, and polyhydroxybutyrate, wherein said bacterium is modified so that activities of D-xylulose-5-phosphate phosphoketolase and/or fructose-6-phosphate phosphoketolase are enhanced. The present invention also provides a method for producing the useful metabolite using the bacterium.

Use of phosphoketolase for producing useful metabolites

There is disclosed a method for producing L-amino acid, for example L-threonine, L-lysine, L-histidine, L-phenylalanine, L-arginine or L-glutamic acid, using a bacterium of the Enterobacteriaceae family, wherein the bacterium has been modified to enhance an activity of D-xylose permease.

Method for producing L-amino acids using bacteria of the enterobacteriaceae family

Method for producing L-amino acids using bacteria of the Enterobacteriaceae family

The present invention provides a method for producing an L-amino acid using a bacterium of the Enterobacteriaceae family, particularly a bacterium belonging to genusor, which has been modified to have glycerol kinase in which feedback inhibition by fructose-1,6-bisphosphate is desensitized, thereby having enhanced ability to utilize glycerol.

Method for producing an L-amino acid by fermentation using a bacterium having an enhanced ability to utilize glycerol

There is disclosed a method for producing an L-amino acid, for example L-threonine, L-lysine, L-histidine, L-phenylalanine, L-arginine, L-tryptophan or L-glutamic acid, using a bacterium of the Enterobacteriaceae family, wherein the bacterium has been modified to enhance an activity of L-arabinose permease.

There is provided a method for producing an L-amino acid using a bacterium of thefamily, particularly a bacterium belonging to the genusor, having the glycogen biosynthesis pathway disrupted.

Method for producing an l-amino acid using a bacterium of the enterobacteriaceae family having a pathway of glycogen biosynthesis disrupted

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Moscow, Russia

Ekaterina Aleksandrovna Slivinskaya