Toudai Tlo, Ltd.

The University of Tokyo

Center for Advanced Science and Technology Incubation, Ltd.

Juntendo University

Eisaku Katayama

Norio Baba

Yoshitaka Kimori

Takuya Kobayashi

Takashi Murayama

Taku Kashiyama

The present invention aims at providing a general-purpose experimental tool which specifically binds to a macromolecular substance that will be a receptor for a specific ligand such as drug, and is applicable throughout various processes to explore the nature of the macromolecular substance. In order to achieve this object, a molecular module has been developed which binds to a target compound and is used for purifying or labeling the target compound, wherein the molecular module has a rod-like spacer substance, an interacting substance that interacts with the target compound, a tag and a labeling substance, the interacting substance being positioned at one end of the rod-like spacer substance, and the tag and the labeling substance being positioned at the other end of the rod-like spacer substance.

Labeled fusion protein

There is provided a three-dimensional image reconstructing apparatus for reconstructing a three-dimensional image of an object. The three-dimensional image reconstructing apparatus includes an image-capturing section that captures a plurality of transmission-type images each of which is represented by densities of different levels, a characteristic region selecting section that selects a plurality of characteristic regions in each of the transmission-type images, a characteristic region distribution calculating section that calculates a spatial distribution of the characteristic regions based on respective positions of the characteristic regions, in each of the transmission-type images, and a three-dimensional image reconstructing section that, when reconstructing the three-dimensional image which shows the three-dimensional structure of the object and in which the densities of different levels are allocated to the whole object by integrating the transmission-type images, allocates the densities of different levels of the transmission-type images to respective positions, in the three-dimensional image, of the characteristic regions based on the spatial distribution of the characteristic regions, so as to reconstruct the three-dimensional image in which a three-dimensional structure in each of the characteristic regions is shown.

Stereoscopic image regenerating apparatus, stereoscopic image regenerating method, and stereoscopic image regenerating program

It is an object of the present invention to acquire 3-dimensional image data that correctly express a structural configuration of the subject by processing the projected image data obtained by projecting the subject toward the plural angles . A shape computing unitcalculates shape data which represent a outline of the subject, using a plurality of 1st image data of the subject obtained by projecting the subject toward the plural angles. A distributing unitgenerates gray-scale density-distributions by spreading and distributing densities shown in gray-scale image of the subject respectively within angles along which said gray-scale image was captured. A second integrating unitgenerates 3-dimensional gray-scale data, which expresses the subject with the 3-dimensional image data, by integrating a plurality of said gray-scale density-distributions generated from a plurality of gray-scale image captured from a plurality of angles. A first integrating unitintegrates the shape data and 3-dimensional gray-scale image. A data processing unitgenerates 3-dimensional image data by extracting only density that exists in perimeter of a shape that the shape data represent, from the 3-dimensional gray-scale data.

Image processing apparatus, image processing method, computer readable medium, and computer program thereof

A projection image data captured from a plurality of angles is processed, and a three-dimensional image data accurately indicating a three dimensional structure for an object is obtained. A shape computing unitcomputes shape data indicating an outline of a subject using a plurality of first image data of the subject captured from a plurality of angles. A distributing unitgenerates a gray-scale density-distribution by extending and distributing density indicated in a gray-scale image of the subject acquired by a projection image capturing apparatus to an angle at which the gray-scale image is captured. The second integrating unitgenerates a three-dimensional gray-scale data indicating the subject with three-dimensional image data by integrating a plurality of gray-scale images acquired from a plurality of angles and a plurality of gray-scale density-distribution. The first integrating unitintegrates the three-dimensional gray-scale image and shape data. The data processing unitgenerates the three-dimensional image data by extracting only the gray-scale data which exists in the circumference of the shape indicated in the shape data from the three-dimensional gray-scale data.

Three-dimensional structure verification supporting apparatus, three-dimensional structure verification method, recording medium, and program therefor

Verification of properness of a modeling theory of an uncrystallized substance or an image processing method is made easy. There includes: a first displaying unit 120 for rotationally displaying an simulated three-dimensionally shaded model image, which is a shaded image of the three-dimensional reconstruction image; and a second displaying unit 140 for displaying the three-dimensional image of the substance acquired by experimental structural analysis, which synchronously rotates with the simulated three-dimensionally shaded model image.

Growing community of inventors

Tokyo, Japan

Eisaku Katayama