Mayo Foundation for Medical Education and Research

Arizona Board of Regents, a Body Corporate

Eileen M McMahon

Marek Belohlavek

Jianming Liang

Nima Tajbakhsh

Hong Wu

Wenzhe Xue

Systems and methods for navigating a catheter and delivering a needle to a desired anatomic location are provided. The system includes an injection catheter that includes a needle slidably exposed from, or retracted into, the catheter lumen. The system further includes a first acoustic marker located at a distal end of the catheter and configured to generate an acoustic signal, and a second acoustic marker located at the distal end of the retractable needle and configured to generate an acoustic signal. The acoustic markers allow, in conjunction with a Doppler ultrasound imaging system, identification and navigation of an injection catheter and delivering a needle to a desired anatomic target location.

Systems and methods for navigating a catheter and delivering a needle

Receiving a plurality of images of a first wall of the patient's heart, the plurality including a first image captured at a time ij and a second image captured at a time t, determining, based on the plurality of images, a first characteristic of movement of at least a wall portion of the first wall during a time period spanning time tand time t, the first characteristic of movement being determined by using one or more image processing techniques, and the first, characteristic of movement being based on at least one of: (i) a shape of the wall portion in the first image and a shape of the wall portion in the second image, and (ii) a location of the wall portion in the first image and a location of the wall portion in the second image: and outputting an indication of the first characteristic of movement.

Systems, methods, and media for monitoring the condition of a patient's heart

A trainable, adaptable system for analyzing functional or structural clinical data can be used to identify a given pathology based on functional data. The system includes a signal processor that receives functional data from a device monitoring a subject and normalizes the functional data over at least one cycle of functional data. The system also includes a neural network having a plurality of weights selected based on predetermined data and receiving and processing the normalized functional data based on the plurality of weights to generate at least one metric indicating a degree of relation between the normalized functional data to the predetermined data. A diagnostic interpretation module is included for receiving the at least one metric from the neural network and classifying the functional data as indicative of the given pathology or not indicative of the given pathology based on a comparison of the at least one metric to at least one probability distribution of a likelihood of the given pathology.

Growing community of inventors

Cocoa, FL, United States of America

Eileen M McMahon