Bacoustics, LLC

Other

Advanced Medicalapplications, Inc.

Celleration, Inc.

Ab Ortho, LLC

Alliqua Biomedical, Inc.

Eilaz Babaev

Michael T Peterson

Alan Van Houten

Menendez Adolfo

Greg Doten

Ashok Kumar

Robert J Wojciechowski

Michael R Afremov

Paul W Schmokel

Adolfo Menendez, Jr

Douglas L Lewis

Jian Ruan

Scott R Banaszewski

Scott C Ecelberger

Manish Kochar

Michael Peterson

The present invention relates to an ultrasound liquid atomization and/or separation system including an ultrasound atomizer and a liquid storage area in communication with the ultrasound atomizer. The ultrasound atomizer has an ultrasound transducer, an ultrasound tip at the distal end of the transducer, a liquid delivery orifice or plurality of liquid delivery orifices, and a radiation surface at the distal end of the tip. The atomizer may include a liquid delivery collar having a liquid receiving orifice and a liquid delivery orifice. The liquid delivery collar may also include a central orifice into which the ultrasound tip may be inserted.

Ultrasonic atomization and/or seperation system

The present invention is directed towards the holding of medical devices during manufacture to enable the application of therapeutic and/or protective coatings. More specifically, the present invention provides medical device holders that securely retain stents and other medical devices during the application of a coating while minimizing compressive and tensile forces applied to the stents. The invention avoids disruptions to coating quality due to holder blockage during coating deposition. The invention discloses an improved device containing a mandrel and frame that may improve coating uniformity by eliminating shadowing from the frame of the medical device holder when applying coatings to stents and other medical devices.

Apparatus for holding a medical device during coating

The present invention relates to an ultrasonic syringe and method of use for delivery and withdrawal of fluids from a human and/or animal patient. The ultrasonic syringe apparatus comprises a generator, a movable ultrasound transducer, a barrel, an ultrasound transducer tip, a radiation surface, an orifice located at the front end of the barrel, and a syringe head. The apparatus may further comprise a channel, a valve located on the distal end of the channel, and an orifice within the side wall which enables fluids to be delivered into the barrel. Ultrasonic waves emitting from the radiation surface induce vibrations within the fluids, sonicating the fluids, thereby eliminating the pain and discomfort associated with receiving injections, reducing and/or eliminating the force required to administer the injection, decreasing delivery time of the fluids into the body, and delivering ultrasonic energy to the tissue via the sonicated fluids.

Ultrasonic syringe method

A medical ultrasound apparatus and associated methods of use is disclosed enabling a relatively non-invasive or minimally invasive method to treat skin or tissue. The apparatus is constructed from an ultrasound tip mechanically coupled to a shaft. The shaft is mechanical coupled to an ultrasound transducer driven by an ultrasound generator. The ultrasound tip possesses at least one radial surface, a cavity, or some other form of a hollowed out area, within at least one of the radial surfaces, and a non-metallic sheath covering portions of the tip so that only the sheath and not the tip would normally contact the patient's skin. The disclosed method of treating spider, reticular or small varicose veins with the apparatus can be practiced by contacting the sheath with the patient's epidermal skin layers and delivering ultrasonic energy released from the various surfaces of the vibrating tip to the skin and/or tissue through direct contact and/or with a coupling fluid focused from a cavity.

Methods for treatment of spider veins

This invention discloses methods and devices using ultrasound energy for use before, during or after surgery for providing a therapeutic effect on nerve tissue. The disclosure describes the use of ultrasound devices consisting of an ultrasound generator, ultrasound transducer and ultrasound horn at least partially enclosed by a shield to enhance neurogenesis on neurons of the central nervous system and other nerve tissue. The shield allows the application of therapeutic levels of ultrasound to nerve tissue to enhance the regeneration of the nerve tissue and mitigate damage to the nerve tissue. The shield serves to protect patient from unwanted contact with portions of the ultrasound horn not being utilized for therapeutic effect. The ultrasound application may be included in devices that have other uses such as a cutting edge for removing tissue.

Ultrasound apparatus and methods for mitigation of neurological damage

Spider vein treatment apparatus

This invention discloses deflector shields to protect an operator from splashing from the use of hand-held ultrasound wound care devices. The deflector shield is for use with an ultrasound generator, ultrasound tip with a radiation surface and a fluid to serve as a coupling medium between the radiation surface and wound surface. The deflector shield is used to protect the operator from splashing fluid and removed tissue. The deflector shield consists of a hub portion and conical portion. The deflector shield is preferably transparent, disposable and easily installed. The deflector shield is preferably useable on several hand-held ultrasound wound care devices.

Deflector shield for use with multiple wound care devices

The present invention relates to the use of a low frequency ultrasonic device for the delivery and activation of collagen based foam sealants to a human and/or animal patient for sealing puncture wounds in vascular tissues. The ultrasonic vascular closure device comprises an ultrasonic generator, an ultrasound transducer, a chamber containing a foam sealant, a transducer tip, a radiation surface, an orifice located at the distal end of the chamber. The foam sealant is ejected into a puncture wound and activated with ultrasonic waves emitting from the radiation surface. The ultrasonic waves induce vibrations within the foam sealant, slightly warming the foam sealants to assist the rapid sealing the puncture. The ultrasonic waves also provide and anesthetic effect for the pain and discomfort from the puncture site.

Ultrasonic vascular closure device

An apparatus and method are provided for generating ultrasonic energy from a non-contact distance from the surface of the wound; and delivering the generated ultrasonic energy to the wound through a gaseous medium. The generated ultrasonic energy has a significantly large amplitude such that the ultrasonic energy has an intensity capable of penetrating the wound tissue to a beneficial depth to provide a therapeutic effect for decreasing the healing time for the wound.

Ultrasonic method and device for wound treatment

An ablative apparatus that can be used to treat atrial fibrillation and other cardiac arrhythmias by ablating cardiac tissue is disclosed. When the distal end of the apparatus reaches the tissue to be ablated, an ablation probe driven by a transducer is vibrated. Scratching the tissue with abrasive members, the vibrating ablation probe is capable of mechanically ablating tissues. This mechanical ablation may be utilized to penetrate epicardial fat, thereby exposing the underlying myocardium. The ablative apparatus may then be used subject the exposed myocardium to mechanical ablation, cryoablation, ultrasonic ablation, and/or any combination thereof.

Ablative ultrasonic-cryogenic apparatus

The present invention relates to a method of treating lumens, cavities, and tissues of the body with a liquid delivered with the use of ultrasound. Delivering a liquid with the use of ultrasound may be accomplished by utilizing a device comprising an ultrasound transducer, an ultrasound horn, a channel running at least partially through said horn, and a dampening grommet at the distal end of the horn (hereafter called the 'delivery device'). The delivery device may further comprise a liquid supply emptying into said channel. Subjecting liquids within the horn of the delivery device to ultrasonic energy accelerates the liquid, thereby creating a higher velocity, low pressure liquid stream. Consequently, the method of the present invention enables the treatment of maladies deep within lumens, cavities, and tissues of the body. The method of the present invention may also be used for douching and/or cleaning lumens, cavities, and tissues of the body.

Method of treating lumens, cavities, and tissues of the body with an ultrasound delivered liquid

An ultrasound assisted liquid blade cutting device such as a scalpel that may be used for routine surgical operations is disclosed in this invention. The ultrasound scalpel comprises an ultrasound generator, ultrasound transducer, transducer tip, a cavity on the transducer tip using a liquid spray shaped to form a cutting surface. The spray serves as a carrier medium for the applied ultrasound energy which enhances the features and performance of the scalpel. Ultrasonic energy transmitted from the transducer tip assists the transport of the liquid to a liquid blade formed outside of the cavity. The ultrasound energy focuses and activates the liquid to allow cutting of tissue with the liquid blade. This device may be utilized for cutting through skin and/other soft tissues during surgical operations, thereby enhancing cutting efficacy, decreasing and/or eliminating necrosis formation.

Ultrasound liquid blade scalpel device

An ultrasound apparatus capable of mixing and/or atomizing fluids is disclosed. The apparatus includes a horn having an internal chamber through which fluids to be atomized and/or mixed flow. Connected to the horn's proximal end, a transducer powered by a generator induces ultrasonic vibrations within the horn. Traveling down the horn from the transducer, the ultrasonic vibrations induce the release of ultrasonic energy into the fluids to be atomized and/or mixed as they travel through the horn's internal chamber. As the ultrasonic vibrations travel through the chamber, the fluids within the chamber are agitated and/or begin to cavitate, thereby mixing the fluids. Upon reaching the front wall of the chamber, the ultrasonic vibrations are reflected back into the chamber, like an echo. The ultrasonic vibrations echoing off the front wall pass through the fluids within the chamber a second time, further mixing the fluids.

Echoing ultrasound atomization and mixing system

An ultrasound apparatus capable of mixing and/or atomizing fluids is disclosed. The apparatus includes a horn having an internal chamber, containing at least one free member, through which fluids to be atomized and/or mixed flow. Connected to the horn's proximal end, a transducer powered by a generator induces ultrasonic vibrations within the horn. Traveling down the horn from the transducer, the ultrasonic vibrations induce the release of ultrasonic energy into the fluids to be atomized and/or mixed as they travel through the internal chamber. As the ultrasonic vibrations travel through the chamber, the fluids within the chamber are agitated and/or begin to cavitate, while the free member moves about the chamber, thereby mixing the fluids. Upon reaching the front wall of the chamber, the ultrasonic vibrations echo off the front wall and pass through the fluids within the chamber a second time, further mixing the fluids.

Mechanical and ultrasound atomization and mixing system

Method and device for the creation of vaccines using ultrasonic waves, comprised of an ultrasound generator and a transducer to produce ultrasonic waves, is disclosed. The transducer has a specific ultrasound tip depending upon the type of delivery method utilized and depending on the shape of the vial containing the solution of the virus, bacterium, or other infectious agent. The apparatus delivers ultrasonic waves to solution either directly through the insertion of the ultrasound tip into the solution, through a coupling medium adjacent to the vial or near the vial, or through an air or gas medium. The ultrasound waves have the effect of destroying the viable virus, bacterium, or other infectious agent and of releasing the appropriate antigens, thus resulting in a vaccine for that virus, bacterium, or other infectious agent.

Growing community of inventors

Minnetonka, MN, United States of America

Eilaz Babaev