Debiopharm Research & Manufacturing Sa

Debiopharm International, S.a.

Eija Lundstrom

Patrick Garrouste

Marie-Anne Bardet

Herve Porchet

Bertrand Ducrey

Frederic Heimgartner

Catherine Curdy

Hervé Porchet

Frédéric Heimgarten

Frédéric Heimgartner

Pharmaceutical composition made of microparticles for the slow release of an active substance at least during a period covering the 6th month after injection of said composition, said composition comprising a group of microparticles made of a copolymer of the PLGA type which incorporate an active substance in the form of a water insoluble peptide salt; said copolymer furthermore comprising at least 75% of lactic acid and an inherent viscosity between 0.1 and 0.9 dl/g, as measured in chloroform at 25&#xb0; C. and at a polymer concentration of 0.5 g/dL; said microparticles furthermore having a size distribution defined as follows: &#x2014;D (v,0.1) is between 10 and 30 micrometers, &#x2014;D (v,0.5) is between 30 and 70 micrometers, &#x2014;D (v,0.9) is between 50 and 1 10 micrometers.

Slow release pharmaceutical composition made of microgranules

Growing community of inventors

Lutry, Switzerland

Eija Lundstrom