Teikoku Hormone Mfg. Co., Ltd.

Eiichiro Shimazawa

Kenyu Shibata

Naoyuki Koizumi

Shigehiro Takegawa

Mamoru Mieda

Nobuaki Yamakoshi

A compound represented by the following formula ##STR1## wherein A represents a hydrogen atom or a lower alkanoyl group, Z represents an oxygen atom or the group ##STR2## in which R represents a hydrogen atom or a lower alkyl group, and X represents a halogen atom, the compound being useful for controlling androgen-dependent diseases, particularly for preventing abortion or for contraception.

Compositions and methods employing 2-oxa- or -aza-pregnan compounds for

A compound represented by the following formula ##STR1## wherein A represents a hydrogen atom or a lower alkanoyl group, Z represents an oxygen atom or the group ##STR2## in which R represents a hydrogen atom or a lower alkyl group, and X represents a halogen atom, the compound being useful for controlling androgen-dependent diseases, particularly for preventing prostatic hypertrophy.

Growing community of inventors

Sagamihara, Japan

Eiichiro Shimazawa