Osaka University

Kyocera Corporation

Panasonic Corporation

Allied Telesis Holdings K.k.

Japan Science and Technology Agency

Japan Advanced Institute of Science and Technology

Valneva

Bio Device Technologies Co., Ltd.

Eiichi Tamiya

Masato Saito

Hideharu Kurioka

Hiroyasu Tanaka

Hiroaki Tachibana

Koji Tsuji

Minoru Aoki

Hiroyuki Kishi

Atsushi Muraguchi

Yuzuru Takamura

Noriyasu Katoh

Shogo Shibuya

Narimasa Iwamoto

Akiko Iiduka

Hiroyuki Yoshikawa

Shuhei Imura

Yuichiro Kiriyama

Masayasu Susuki

Ryou Tanaka

Tatsurou c/o Tokyo Institute Of Technology Endou

Naoki Nagatani

Teruko Yui

A purpose is to provide a monitoring system to monitor whether there is a substance to be monitored in the air, and a detecting device used in the monitoring system. The monitoring system includes a detecting device, an analyzing device, and an abnormality notification system. The detecting device determines whether the air is in an abnormal state on the basis of an output signal from an abnormality detection sensor, pours liquid to be inspected, into which the air is sucked and liquefied, into a previously-installed reagent container when determining the abnormal state, generates mixed liquid in which a reactant in the reagent container and the poured liquid to be inspected are mixed, and drops the generated mixed liquid to an electrode of the analyzing device. The analyzing device determines existence/non-existence of a substance to be monitored on the basis of the mixed liquid dropped to the electrode, and gives a predetermined notification to the abnormality notification system when determining that there is the substance to be monitored. The abnormality notification system gives a predetermined notification when receiving the notification from the analyzing device.

Monitoring system and detecting device

A thermal convection generating device () that generates thermal convection of a liquid by heating or cooling the liquid and applying centrifugal force to the liquid, the thermal convection generating device including: a stage () to which a thermal convection generating chip () is attachable and detachable, the thermal convection generating chip including a disk-like substrate () and a thermal convection pathway () formed in a surface of the disk-like substrate that is perpendicular to an axis (AX) of the disk-like substrate, and being configured to rotate about the axis of the disk-like substrate to apply centrifugal force to a liquid in the thermal convection pathway; a heat controller () that heats or cools a portion of the thermal convection pathway; a motor () that drives the thermal convection generating chip to rotate about the axis; and a controller () that controls the heat controller and the motor.

Thermal convection generating chip, thermal convection generating device, and thermal convection generating method

The present invention provide a method for detecting a test substance utilizing a color development caused by an enzyme reaction, or a color development caused by a specific interaction such as an antigen-antibody reaction and an enzyme reaction, the test substance being detected rapidly, sensitively and quantitatively without using a spectroscopic measurement device. The method for measuring a concentration of a test substance by the present invention comprises the steps of: generating a peroxide from the test substance; obtaining a polymerized substance by bringing an oxidoreductase for producing a polymerized substance and a substrate of the oxidoreductase for producing a polymerized substance into contact with the peroxide; and irradiating the polymerized substance with light to record a temporal variation information of an intensity of scattered light generated from an irradiation point.

Method for measuring concentration of test substance, and detection apparatus

The present invention provides a surface acoustic wave sensor capable of suitably controlling the flow of a liquid sample onto IDT electrodes. A surface acoustic wave sensor has a piezoelectric substrate, a first IDT electrode and a second IDT electrode which are located on the upper surface of the piezoelectric substrate and are separated from each other while sandwiching a detection part on the piezoelectric substrate therebetween, and the cover which forms the space being on the first IDT electrode, second IDT electrode, and the detection part and straddling them. On the lower surface of the cover, the detection part-facing surface facing the detection part has a smaller contact angle to the liquid sample than that of a pair of electrode-facing surfaces facing the first IDT electrode and second IDT electrode.

Surface acoustic wave sensor

A thermal convection generating chip () includes a rotatory body (), a thermal convection pathway () provided in the rotatory body (), and a supply path (A toC) that supplies a liquid to the thermal convection pathway (). The supply path (A toC) includes a liquid receiving section () that receives the liquid and a suction passage () that provides communication between the liquid receiving section () and the thermal convection pathway (). The suction passage () has a first region () extending between a midsection of the suction passage () and the thermal convection pathway (), and a second region () extending between the midsection and the liquid receiving section (). The liquid in the first region () is separated from the liquid in the second region () through rotation of the rotatory body () to be supplied to the thermal convection pathway ().

Thermal convection generating chip and liquid measuring device

A sensor is provided with a sensor element which outputs a signal in accordance with a detected object contained in a specimen positioned on a detection part in an element surface and with a package which accommodates the sensor element inside it and has a passage including a space positioned on the element surface. A lower surface of the passage has the element surface and a lower surface of an inflow passage extending toward the space, and a gap is positioned between the lower surface of the inflow passage and the element surface. The element surface is positioned above the lower surface of the inflow passage.

Sensor

A nucleic acid amplification device includes: an introduction unit into which a reaction solution including a target nucleic acid is introduced; a nucleic acid amplification reaction section in which at least two temperature zones of different temperature are present, for amplifying the target nucleic acid included in the reaction solution introduced into the introduction unit; and a channel arranged to pass back and forth or in cyclic fashion through the at least two temperature zones, and having a capillary force transport mechanism for feeding the reaction solution by capillary force.

Nucleic acid amplification device, nucleic acid amplification apparatus, and nucleic acid amplification method for transporting reaction solution including target nucleic acid via capillary force to amplify target nucleic acid

The present invention provides a surface acoustic wave sensor capable of suitably controlling the flow of a liquid sample onto IDT electrodes. A surface acoustic wave sensorhas a piezoelectric substrate, a first IDT electrode and a second IDT electrode which are located on the upper surface of the piezoelectric substrate and are separated from each other while sandwiching a detection part (detection region) on the piezoelectric substrate there between, and the cover which forms the space being on the first IDT electrode, second IDT electrode, and detection part and straddling them. On the lower surface of the cover, the detection part-facing surface (lower surface of the film) facing the detection part has a smaller contact angle to the liquid sample than that of a pair of electrode-facing surfaces (lower surface of the cover body) facing the first IDT electrode and second IDT electrode.

A microfluidic device includes a channel through which a reaction solution flows. The channel passes through a reaction section having a plurality of temperature zones set at predetermined different temperatures. The channel includes, at least in the reaction section, a region where a cross-sectional area decreases in a feeding direction of the reaction solution.

Microfluidic device

Growing community of inventors

Osaka, Japan

Eiichi Tamiya