Emisphere Technologies, Inc.

Entera Bio Ltd.

Other

Sloan-kettering Institute for Cancer Research

Oramed Ltd.

Newel Dexter LLC

Ehud Arbit

Michael M Goldberg

Miriam Kidron

Steven Minh Dinh

Russ Weinzimmer

Isaac Rubinstein

Ziv Harish

Michael Goldberg

Shingai Majuru

Puchun Liu

Vivien Wong

Richat Abbas

Donald J Sarubbi

Nai Fang Wang

Gene R DiResta

Shingal Majuru

T Cooper Woods

Jongbin Lee

Vivian Wong

This invention provides compositions comprising a protein, an absorption enhancer, a protease inhibitor, method for treating diabetes mellitus, comprising administering same, and methods for oral administration of a protein with an enzymatic activity, comprising orally administering same.

Methods and compositions for oral administration

Provided herein are oral pharmaceutical compositions containing a GLP-1 analogue and/or insulin for treating and reducing the incidence of nonalcoholic fatty liver disease (NAFLD), hepatic steatosis, and sequelae thereof, and methods of utilizing same.

Methods and compositions for treating NAFLD, hepatic steatosis, and sequelae thereof

An allergy skin test device is disclosed that causes less pain than commonly used devices that include multi-point sharp puncture heads. The allergy skin test device incorporates multiple dull pressure heads distributed amongst the sharp multi-point sharp puncture heads, each dull pressure head activating a neurological pain gate that reduces pain sensation typically caused by the neighboring multi-point head when it engages the skin.

Reduced-pain allergy skin test device

The present invention provides a topical composition comprising (a) at least one delivery agent compound and (b) a cromoglycic acid compound. Methods of treatment, and methods of preparing the topical composition are also provided.

Topical cromolyn formulations

This invention provides compositions comprising a protein, an absorption enhancer, a protease inhibitor, methods for treating diabetes mellitus, comprising administering same, and methods for oral administration of a protein with an enzymatic activity, comprising orally administering same.

Methods and compositions for oral administration of insulin

The present invention provides a composition (e.g., a pharmaceutical composition) comprising at least one delivery agent compound and glucagon. Preferably, the composition includes a therapeutically effective amount of glucagon and the delivery agent compound. The composition of the present invention facilitates the delivery of glucagon and increases its bioavailability compared to administration without the delivery agent compound.

Intraoral dosage forms of glucagon

Methods for treating impaired glucose tolerance and early and late stage diabetes in mammals, for prophylactically sparing &#x3b2;-cell function, aiding in preventing &#x3b2;-cell death, preventing the onset of overt diabetes in a mammal with type 2 diabetes, treating the current level of glycemic control dysfunction of a mammal with impaired glucose tolerance or diabetes, comprising orally administering insulin and a delivery agent that facilitates insulin absorption from the gastrointestinal tract at the time of or shortly before mealtime, e.g., within about 10 minutes prior to ingestion of a meal, on a chronic basis. The methods also comprise, in addition to administering a rapid-acting insulin to provide a first insulin peak, administering a slow acting insulin to provide a second insulin peak occurring at a later time but of a longer duration. These methods achieve improved glycemic control without the risks of hypoglycemia, hyperinsulinemia and weight gain and the need for frequent blood glucose monitoring that are normally associated with insulin therapy.

Oral insulin therapies and protocol

A breast examination system is disclosed that facilitates normalized quantitative comparison of results from multiple examinations performed under differing conditions, such as different viewing angles. The proposed system can operate on a camera-equipped smart-phone, a camera-equipped desk-top computer, or on a dedicated device to perform a guided breast cancer examination, and then store results of the examination in a normalized format that allows effective quantitative comparison to historic results, thereby detecting changes and trends. The results can be stored on the local device, or on a web-based server, providing various data comparison, data management, and data interpretation services in a secure and controlled manner.

Software product for breast examination result mapping, recording, comparing, and/or tracking

An oral dosage form comprises cromolyn sodium (sodium or disodium cromoglycate), and an acylated amino acid delivery agent.

Growing community of inventors

Englewood, NJ, United States of America

Ehud Arbit