Duke University

Ehsan Samei

Xiaoyu Tian

Paul Segars

Jeremiah W Sanders

Yuan Lin

Disclosed herein are systems and methods for determining quality metrics of images based on an edge gradient profile and characterizing regions of interest in an image or images. According to an aspect, a method includes using an imaging device to acquire one or more images including at least a portion of an organ of a subject. The method also includes computing an edge profile across an organ interface of a subject. The method also includes computing an edge gradient profile from the edge profile of a subject. The method also includes computing a image quality metric related to the spatial resolution of the image or images from the edge gradient profile. The method also includes defining multiple regions of interest within the portion of the organ. Further, the method includes characterizing the regions of interest based on predetermined criteria. The method also includes presenting the characterization of the edge gradient profile and characterization of the regions of interest to a user.

Systems and methods for determining quality metrics of an image or images based on an edge gradient profile and characterizing regions of interest in an image or images

Systems and methods for estimating irradiation dose for patient application based on a radiation field model and a patient anatomy model are disclosed. According to an aspect, a method includes providing a database of patient anatomy models. The method also includes providing a radiation field model of an X-ray system. Further, the method includes receiving a measure of an anatomy of a patient. The method also includes determining a patient anatomy model among the patient anatomy models that matches or is similar to the anatomy of the patient based on the measure of the patient and a corresponding measure of each of the patient anatomy models. The method also includes estimating an irradiation dose for application to the patient by the X-ray system based on the radiation field model and the determined patient anatomy model.

Systems and methods for estimating irradiation dose for patient application based on a radiation field model and a patient anatomy model

Spectral estimation and poly-energetic reconstructions methods and x-ray systems are disclosed. According to an aspect, a spectral estimation method includes using multiple, poly-energetic x-ray sources to generate x-rays and to direct the x-rays towards a target object. The method also includes acquiring a series of poly-energetic measurements of x-rays from the target object. Further, the method includes estimating cross-sectional images of the target object based on the poly-energetic measurements. The method also includes determining path lengths through the cross-sectional images. Further, the method includes determining de-noised poly-energetic measurements and de-noised path lengths based on the acquired poly-energetic measurements and the determined path lengths. The method also includes estimating spectra for angular trajectories of a field of view based on the de-noised poly-energetic measurements and the path lengths.

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Durham, NC, United States of America

Ehsan Samei