Allergan, Inc.

Apollo Endosurgery, Inc.

Edwin Kayda

Justin J Schwab

Zachary Dominguez

Ethan W Franklin

Bastien Mandaroux

Dimitrios Stroumpoulis

Jason Metzner

Michael Augarten

Christopher S Mudd

Greg Nitka

Tracy Ann Perry

Rui Avelar

Skin can be treated by piercing skin with a plurality of needles of an injection device and ejecting a dose of fluid therethrough. The device can include a housing, a plunger disposed in the housing, a cartridge disposed in the housing, and one or more dosing chambers. The plurality of needles can be coupled to the housing and be in fluid communication with the cartridge. Advancement of the plunger can cause a dose of fluid to be ejected from the plurality of needles.

Devices for injection and dosing

A skin treatment can include applying a microneedle device to a region of the skin so that microneedles of the device penetrate the stratum corneum. The arrangement of microneedles can have first microneedles with a first length and second microneedles with a second length, different from the first length. The first and second microneedles can be formed from a mixture of a polymeric material and an active agent beneficial to skin. After the device is applied to the skin, the first and second microneedles can be released below the skin surface, followed by dissolution of the first and second microneedles.

Dissolvable microneedles for skin treatment

A skin treatment device is provided including bioerodible polymeric microneedles which are designed to more effectively deliver beneficial agents to the skin. The device includes a flexible substrate and an arrangement, for example, an array, of microneedles projecting from the substrate.

Described herein are syringe accessories that can be attached to standard syringes. These accessories utilize one or more mechanisms that can provide at least one additional sensory feedback to the user when performing an aliquot or dosed injection. In other embodiments, the accessories can prevent overdosing.

Mechanical syringe accessory

Injection devices are provided which include a handpiece capable of housing a cartridge containing an injectable composition, and a head coupled to the handpiece and housing a plurality of retractable needles and a dosing mechanism. Methods of treating skin surfaces are also provided.

Methods and devices for use in reducing the appearance of dimpled skin or other undesirable appearance of skin in a cellulitic region of a patient are provided. The methods include the steps of disrupting fibrous septae located beneath the skin of a cellulitic region and introducing a composition beneath the skin, the composition being effective to reduce or prevent regrowth of the fibrous septae.

Devices and methods for reducing the appearance of cellulite

A device is provided for introducing into a patient a combination of adipose tissue and an additive, for example, a hydrogel additive. The device includes a fat cartridge, an additive cartridge containing an additive, and a housing configured to receive, in a side-by-side manner, the fat cartridge and additive cartridge. A mixing tip may be included for causing mixing of the cartridge components prior to extrusion from a needle or cannula.

Syringe for mixing and dispensing adipose tissue

An implantable injection port comprises a base. A first gear is coupled to the base, and a first anchor is coupled to the first gear. A second gear is coupled to the base, and a second anchor is coupled to the second gear. A top portion of the injection port is spaced apart from the base of the port and has a first plurality of top teeth that engage with a first plurality of gear teeth on the first gear. This engagement occurs prior to rotation of the second gear. The top portion rotates, which causes rotation of the first gear, which in turn causes movement of the first anchor through the anchor opening of the base and into the tissue of the patient. The first gear and the second gear rotate non-simultaneously.

Growing community of inventors

Santa Barbara, CA, United States of America

Edwin Kayda