Maxion Therapeutics Limited

Iontas Limited

Edward William Masters

Tim Luetkens

Sachin Badrinath Surade

John Mccafferty

Aneesh Karatt Vellatt

Damian Colin Bell

Binding members for sodium channel Nav1.7 and their use in medicine including for treatment of pain or epilepsy. Binding members comprise a fusion protein containing a Nav1.7-binding peptide, e.g., venom toxin peptide or knottin ('donor diversity scaffold domain') inserted within an antibody variable domain (“recipient diversity scaffold domain”), and a partner domain (e.g., antibody variable domain), optionally wherein the partner domain enhances specificity of binding to Nav1.7 over other sodium channels.

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Sawston, United Kingdom

Edward William Masters