Merck + Co., Inc.

Other

Edward Walton

Burton G Christensen

Robert B Morin

Richard L Tolman

Wallace T Ashton

Burton A Christensen

The invention is a bracket having a resilient flange. The bracket attaches to the periphery of a room partition defining an orifice. The bracket provides a secure mounting location for an air diffuser and holds the box associated with the diffuser firmly in place allowing one person to install the diffuser and the box within an orifice.

Device for mounting air diffusers and boxes to room partition orifices

Pyrimidines having a fused cyclopropane ring in the side chain and the heterocyclic isosteres of said pyrimidines, which have antiviral activity, especially against viruses of the herpes class.

Pyrimidine derivatives as antiviral compounds

An orthopedic chair for a physically impaired person is provided and consists of a seat, backrest, armrests, footrests and a tray that are readily adjustable in various attitudes to conform to the unique requirements of the physically impaired person. The chair also has casters and an adjustable rear handle so that the chair can be portable.

Orthopedic chair

Purines and pyrimidines having a fused cyclopropane ring in the side chain and the heterocyclic isosteres of said purines and pyrimidines have antiviral activity, especially against viruses of the herpes class.

Purine derivatives

Thienamycin sulfoxide (I, n=1), Thienamycin sulfone (I, n=2), and their pharmaceutically acceptable salts are disclosed to be useful as antibiotics: ##STR1## Also disclosed are processes for the preparation of such compounds, pharmaceutical compositions comprising such compounds, and methods of treatment comprising administering such compounds and compositions when an antibiotic effect is indicated.

Thienamycin sulfoxide and sulphone

3-(.beta.-aminoethylidene)-7-oxo-4-oxaazabicyclo [3.2.0]heptane-2-carboxylic acid and derivatives thereof having the structural formula: ##STR1## and the pharmaceutically acceptable salt, ester and amide derivatives thereof are disclosed to be useful as antibiotics. Also disclosed are processes for the preparation of such compounds; pharmaceutical compositions comprising such compounds; and methods of treatment comprising administering such compounds and compositions when an antibiotic effect is indicated.

3-(.beta

3-(.beta.-aminoethylidene)-6-(.alpha.-hydroxyethyl)-7-oxo-4-oxaazabicyclo[3 .2.0]heptane-2-carboxylic acid having the structural formula: ##STR1## and the pharmaceutically acceptable salt, ester and amide derivatives thereof are disclosed to be useful as antibiotics. Also disclosed are processes for the preparation of such compounds; pharmaceutical compositions comprising such compounds; and methods of treatment comprising administering such compounds and compositions when an antibiotic effect is indicated.

3-(.beta.-Aminoethylidene)-6-(.alpha.-hyd

3-(.beta.-Hydroxyethylidene)-6-(.alpha.-Hydroxyethyl)-7-oxo-4-oxaazabicyclo [3.2.0]heptane-2-carboxylic acid having the structural formula: ##STR1## and the pharmaceutically acceptable salt, ester and amide derivatives thereof are disclosed to be useful as antibiotics. Also disclosed are processes for the preparation of such compounds; pharmaceutical compositions comprising such compounds; and methods of treatment comprising administering such compounds and compositions when an antibiotic effect is indicated.

Growing community of inventors

Scotch Plains, NJ, United States of America

Edward Walton