Cambridge Polymer Group, Inc.

The General Hospital Corporation

Teknor Apex Company

Edward T Kopesky

Ebru Oral

Orhun K Muratoglu

Martin F Van Buren

Kevin Cai

Biing-Lin Lee

Gavin J C Braithwaite

Orthun K Muratoglu

Jason Berlin

The present invention relates to methods for making cross-linked oxidation-resistant polymeric materials and preventing or minimizing in vivo elution of antioxidant from the antioxidant-containing polymeric materials. The invention also provides methods of doping polymeric materials with a spatial control of cross-linking and antioxidant distribution, for example, vitamin E (&#x3b1;-Tocopherol), and methods for extraction/elution of antioxidants, for example, vitamin E (&#x3b1;-tocopherol), from surface regions of antioxidant-containing polymeric materials, and materials used therewith also are provided.

Methods for making oxidation-resistant cross-linked polymeric materials

The invention provides methods of making hydrolyzed cross-linked polyvinyl alcohol (PVA) hydrogels by polymerizing vinyl acetate (VAc) monomers to polyvinyl acetate (PVAc) polymer network by chemical-crosslinking and hydrolysis. The invention also provides methods for including pendant chains in the hydrogel during the polymerization process. Materials produced and use of the cross-linked hydrolyzed PVA hydrogels also are disclosed herein.

Hydrolyzed hydrogels

Polyolefin based sealing element compositions with good oxygen barrier properties particularly suitable for forming sealing elements, for example gaskets and cap liners that are especially useful for sealing containers having products such as liquids or food-stuffs therein. The compositions when formed as sealing elements do not appreciably contribute taste and/or odor to a packaged product including the sealing element. The compositions have desirable rheological properties and are thus readily processable at various temperatures.

Sealing elements and sealing element compositions

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Arlington, MA, United States of America

Edward T Kopesky