Leland Stanford Junior University

Cs Fluids, Inc.

Other

Integra Lifesciences Corporation

Eunoe, Inc.

Edward Rubenstein

David L Karshmer

Elliott C Levinthal

Tom Saul

Jaime Salvador Vargas

Jaime S Vargas

Kevin Vincent Grimes

E Barrie Hughes

Robert Hofstadter

Elliot C Levinthal

Tom A Saul

The present disclosure provides synthesized peptides containing azetidine-2-carboxylic acid (Aze), methods for detecting antibodies to peptides containing Aze, and methods for diagnosing conditions associated with misincorporation of Aze into host proteins.

Compositions, systems and methods for the diagnosis, prevention and treatment of disorders associated with azetidine-2-carboxylic acid

Methods and systems for detecting azetidine-2-carboxylic acid (Aze) in food consumable by humans and animals are provided. Also provided are methods and systems for inactivating Aze in food and byproducts, as well as other methods for the diagnosis, prevention, and treatment of disorders associated with Aze.

A method treats a patient for adult-onset dementia of the Alzheimer's type by removing a portion of the patient's cerebrospinal fluid, preferably (although not necessarily) by transporting the fluid to another portion of the patient's body. An apparatus for removing cerebrospinal fluid includes (1) a conduit with a first opening and a second opening, the first opening of the conduit being disposed in fluid communication with a space within a patient's subarachnoid space, the second opening being disposed in fluid communication with another portion of the patient's body; and (2) a flow rate control device attached to the conduit.

Internally powered CSF pump systems and methods

A method for treating a patient for adult-onset dementia of the Alzheimer's type by removing a portion of the patient's cerebrospinal fluid, preferably (although not necessarily) by transporting the fluid to another portion of the patient's body. The invention also provides an apparatus for removing cerebrospinal fluid including (1) a conduit with a first opening and a second opening, the first opening of the conduit being adapted to be disposed in fluid communication with a space within a patient's subarachnoid space, the second opening being adapted to be disposed in fluid communication with another portion of the patient's body; and (2) a flow rate control device attached to the conduit.

Method and apparatus for treating adult-onset dementia of the Alzheimer's type

Provided are compositions comprising nonprotein amino acids and modified amino acids, as well as methods for the use of nonprotein amino acids and modified amino acids in inhibiting the growth of infective agents. In one embodiment the compounds and compositions may be used for treating an infection in a human or animal. For example, infectious agents include resistant strains of Acinetobacter, Klebsiella, Serratia,,and,vancomyocin-resistant enterococci and multi-drug resistant mycobacteria, and other emerging resistant organisms. The compounds and methods are useful for treating infections caused by organisms, including viral pathogens, fungi, yeast, helminths or protozoans. The nonprotein amino acids and modified amino acids may be administered by any route known in the air, such as parenterally, orally, by inhalation or topically, and optionally may be administered in a carrier, such as a polymeric carrier.

Methods for the use of nonprotein amino acids as therapeutic agents

A method for treating a patient for adult-onset dementia of the Alzheimer's type by removing a portion of the patient's cerebrospinal fluid, preferably (although not necessarily) by transporting the fluid to another portion of the patient's body. The invention also provides an apparatus for removing cerebrospinal fluid including (1) a conduit with a first opening and a second opening, the first opening of the conduit being adapted to be disposed in fluid communication with a space within a patient's arachnoid membrane, the second opening being adapted to be disposed in fluid communication with another portion of the patient's body; and (2) a flow rate control device attached to the conduit.

Method and apparatus for treating adult-onset dementia of the

Non-invasive angiography is provided through use of monochromatized synchrotron radiation in a dichromographic procedure. A small quantity of an iodinated compound is introduced into the blood stream of a patient. An X-ray picture of a blood vessel such as the coronary artery can be produced by directing synchrotron radiation from a storage ring source at first and second selected wavelengths or energy levels through the blood vessel, detecting the attenuated radiation to obtain first and second signals representative of the attenuated radiation, and logarithmically subtracting the two signals to essentially eliminate all background contrast. Due to the K-absorption edge of iodine the resulting signal will emphasize the blood vessel containing the iodine.

Growing community of inventors

Hillsborough, CA, United States of America

Edward Rubenstein